Correlations Between Serum IL33 and Tumor Development: a Meta-analysis

Abstract

<b>Background:</b> Interleukin-33 (IL-33) has recently been implicated in tumor development. <br/><b>Methods</b>: Datawas obtained from PubMed, EMBASE, Clinical trial, Cochrane Library, Web of Science, CNKI and Wanfangdatabases. After quality assessment and data extraction, a meta-analysis was performed using Review Manager5. 2 software. <br/><b>Results</b>: There were eight documents included in this meta-analysis. The results showed IL33 levelsto be higher in tumor patients than that in health people, but no correlations tumor stage, metastasis and survivaltime of tumor patients were evident. <br/><b>Conclusion</b>: IL33 may be useful as an alarm factor in tumor detection andprognosis.