Volume 15, Issue 8
مرور بر اساس
ارسال های اخیر
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A Functional SNP in the MDM2 Promoter Mediates E2F1 Affinity to Modulate Cyclin D1 Expression in Tumor Cell Proliferation
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: The MDM2 oncogene, a negative regulator of p53, has a functional polymorphism in thepromoter region (SNP309) that is associated with multiple kinds of cancers including non-melanoma skincancer. SNP309 ...
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Nitric Oxide Synthase 3 Gene Variants and Colorectal Cancer: a Meta-Analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: Colorectal cancer (CRC) is the worldwide disease which causes enormous losses every year.Recent studies suggested that environmental and gene factors might be the etiologies in increasing the risk ...
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Prognostic Value of Hematologic Parameters in Patients with Metastatic Renal Cell Carcinoma Using Tyrosine Kinase Inhibitors
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: The prognostic significance of the neutrophil-to-lymphocyte ratio for progression free survivalin patients with metastatic renal cell carcinoma is unclear. Materials and Methods: We retrospectively ...
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Retrograde Analysis of Clinical Characteristics of Bone Metastasis in 1,031 Cases of Preliminarily Diagnosed Nasopharyngeal Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Purpose: To explore the clinical characteristics of bone metastasis (BM) in a large sample of preliminarilydiagnosed nasopharyngeal carcinomas (NPCs). Methods: The sample consisted of 1,031 patients diagnosed ...
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CYP3A4 Expression in Breast Cancer and its Association with Risk Factors in Mexican Women
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: In Mexico, breast cancer (BCa) is the leading type of cancer in women. Cytochrome P450(CYP450) is a superfamily of major oxidative enzymes that metabolize carcinogens and many antineoplasticdrugs. In ...
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Interactions between Filamin A and MMP-9 Regulate Proliferation and Invasion in Renal Cell Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)This study aimed to analyze the expression, clinical significance of filamin A (FLNA) in renal cell carcinoma(RCC) and biological effects in a cell line by regulating FLNA expression. Immunohistochemistry and Westernblotting ...
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Is the Tumor Infiltrating Natural Killer Cell (NK-TILs) Count in Infiltrating Ductal Carcinoma of Breast Prognostically Significant?
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Purpose: The aim of this study was to investigate the prognostic significance of the CD56+NK-TIL countin infiltrating ductal carcinoma (IDC) of breast. Material and Methods: Immunohistochemistry (IHC) wasperformed ...
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Establishment of and Comparison between Orthotopic Xenograft and Subcutaneous Xenograft Models of Gallbladder Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: Gallbladder carcinoma (GBC) is the most common carcinoma of the biliary system. Among itsresearch models, orthotopic xenograft models, important research tools, have been rarely reported in the ...
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MiR-133b Acts as a Tumor Suppressor and Negatively Regulates TBPL1 in Colorectal Cancer Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Introduction: MicroRNAs have emerged as post-transcriptional regulators that are critically involved intumorigenesis. This study was designed to explore the effect of miRNA 133b on the proliferation and ...
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HPV Detection and Genotyping in Vulvar Squamous Cell Carcinoma in Northern Thailand
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: The study was aimed to evaluate the prevalence and genotype distribution of HPV infection invulvar squamous cell carcinoma (SCC) in northern Thailand and the clinicopathological difference with regardto ...
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Association between RASSF1A Ala133Ser Polymorphism and Cancer Susceptibility: A Meta-Analysis Involving 8,892 Subjects
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: Published studies on the association between the Ras Association Domain Family 1 isoform A(RASSF1A) Ala133Ser polymorphism and cancer susceptibility have yielded conflicting results. Thus, a metaanalysiswas ...
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Cancer: Scenario and Relationship of Different Geographical Areas of the Globe with Special Reference to North East-India
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: Cancer is becoming the most important public health burden around the globe. As per theGLOBOCAN 2008 estimates, about 12.7 million cancer cases and 7.6 million cancer deaths were estimatedto have occurred ...
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Lack of Efficacy of Tai Chi in Improving Quality of Life in Breast Cancer Survivors: a Systematic Review and Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: It is controversial whether Tai Chi (TC) benefits breast cancer survivors (BCS) on quality of life(QoL). We therefore undertook a meta-analysis to assess this question. Materials and Methods: ...
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Rice Bran Phytic Acid Induced Apoptosis Through Regulation of Bcl-2/Bax and p53 Genes in HepG2 Human Hepatocellular Carcinoma Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Phytic acid (PA) has been reported to have positive nutritional benefits and prevent cancer formation. Thisstudy investigated the anticancer activity of rice bran PA against hepatocellular carcinoma (HepG2) cells.Cytotoxicty ...
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Population Based Study of the Association Between Binge Drinking and Mortality from Cancer of Oropharynx and Esophagus in Korean Men: the Kangwha Cohort Study
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)We assessed the association between frequency of heavy binge drinking and mortality from oropharynxand esophagus cancer after controlling for the total volume of alcohol intake among Korean men. The cohortcomprised 2,677 ...
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How to Explain the Contradiction of microRNA 200c Expression and Survival in Solid Tumors?: a Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)MicroRNA 200c is a microRNA 200 family member that plays an important role in regulation of the epithelialto-mesenchymal transition (EMT). The prognostic value of microRNA 200c in solid tumors remains controversialbecause ...
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Different Immunology Mechanisms of Phellinus igniarius in Inhibiting Growth of Liver Cancer and Melanoma Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)To assess inhibition mechanisms of a Phellinus igniarius (PI) extract on cancer, C57BL/6 mice were orallytreated with PI extractive after or before implanting H22 (hepatocellular carcinoma ) or B16 (melanoma) cells.Mice ...
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Schedule-Dependent Effects of Kappa-Selenocarrageenan in Combination with Epirubicin on Hepatocellular Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Hepatocellular carcinoma (HCC) has a relatively higher incidence in many countries of Asia. Globally, HCChas a high fatality rate and short survival. Epirubicin, a doxorubicin analogue, may be administered alone or ...
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CCDC26 Gene Polymorphism and Glioblastoma Risk in the Han Chinese Population
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: Glioblastoma (GBM) is an immunosuppressive tumor whose median survival time is only 12-15 months, and patients with GBM have a uniformly poor prognosis. It is known that heredity contributes toformation ...
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Multicenter Analysis of Gestational Trophoblastic Neoplasia in Turkey
(West Asia Organization for Cancer Prevention (WAOCP), 2014-08-01)Background: To evaluate the incidence, diagnosis and management of GTN among 28 centers in Turkey. Materials andMethods: A retrospective study was designed to include GTN patients attending 28 centers ...
