مرور Volume 19, Issue 7 بر اساس تاریخ انتشار
در حال نمایش موارد 1 - 10 از 10
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Repairing effects of interleukin 11 (IL-11) towards high dose methotrexate-induced rat small intestinal mucositis and its impacts on T-lymphoblastic leukemia cell line
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): To investigate the efficacy of interleukin 11 (IL-11) towards the high dose methotrexate (HDMTX)-concurrent rat small intestinal mucositis and its impacts on the proliferation of the human T-lymphoblastic ...
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Screening of DFNB3 in Iranian families with autosomal recessive non-syndromic hearing loss reveals a novel pathogenic mutation in the MyTh4 domain of the MYO15A gene in a linked family
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): Non-syndromic sensorineural hearing loss (NSHL) is a common disorder affecting approximately 1 in 500 newborns. This type of hearing loss is extremely heterogeneous and includes over 100 loci. Mutations in ...
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Effects of valproic acid and pioglitazone on cell cycle progression and proliferation of T-cell acute lymphoblastic leukemia Jurkat cells
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignant tumor. Administration of chemical compounds influencing apoptosis and T cell development has been ...
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Acute stress does not affect the impairing effect of chronic stress on memory retrieval
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): Due to the prevalence and pervasiveness of stress in modern life and exposure to both chronic and acute stresses, it is not clear whether prior exposure to chronic stress can influence ...
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Methylation and mRNA expression levels of P15, death-associated protein kinase, and suppressor of cytokine signaling-1 genes in multiple myeloma
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): The aim of this study was to investigate the methylation status and mRNA expression levels of P15, death-associated protein kinase (DAPK), and suppressor of cytokine ...
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Immune cell distribution and immunoglobulin levels change following sciatic nerve injury in a rat model
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): To investigate the systemic and local immune status of two surgical rat models of sciatic nerve injury, a crushed sciatic nerve, and a sciatic nerve transection Materials ...
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Chloride channel protein 2 prevents glutamate-induced apoptosis in retinal ganglion cells
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): The purpose of this study was to investigate the role of chloride channel protein 2 (ClC-2) in glutamate-induced apoptosis in the retinal ganglion cell line (RGC-5). Materials ...
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Current progress in the development of therapeutic vaccines for chronic hepatitis B virus infection
(Mashhad University of Medical Sciences, 2016-07-01)Chronic hepatitis B is still a major public health issue despite the successful prophylactic vaccination attempts. Chronicity of hepatitis B virus(HBV) is mainly due to its ability to debilitate host's immune system. ...
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Loss of heterozygosity and microsatellite instability as predictive markers among Iranian esophageal cancer patients
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): Variation in microsatellite sequences that are dispersed in the genome has been linked to a deficiency in cellular mismatch repair system and defects in several genes of this system ...
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C-Kit expression in the gallbladder of guinea pig with chronic calculous cholecystitis and the effect of Artemisia capillaris Thunb on interstitial cells of Cajal
(Mashhad University of Medical Sciences, 2016-07-01)Objective(s): To study the c-Kit expression in the gallbladder of cholesterol lithogenic guinea pig model and the effect of Artemisia capillaris Thunb ...
