Objective: To explore whether monoclonal antibodies against stathmin and the chemotherapuetic agentpaclitaxel have synergenic effects in inhibiting growth and inducing apoptosis in human QG-56 cells. ...

Background: Hepatocellular carcinoma (HCC), the main malignant tumor of the liver, is very commonand highly lethal. The aim of this study was to determine its clinicopathologic characteristics and risk factorsin ...

Tumor metastasis remains the principal cause of treatment failure and poor prognosis in patients withcolorectal cancer. It is a multistage process which includes proteolysis, motility and migration of cells, proliferationin ...

Background: This study aimed to research the awareness of screening colonoscopy (SC) among patientswith colorectal cancer (CRC) and their relatives. Methodology: A questionnaire form including information andbehavior ...

Background: Many studies have investigated the association between glutathione S-transferase T 1 (GSTT1)null genotype and risk of prostate cancer, but the impact of GSTT1 null genotype in Asians is still unclear ...

Considerable research has been conducted concerning galectin-9 and carcinomas, but little information isavailable about any relation with the hepatocellular carcinoma. In this study, we employed a small interferingRNA ...

Objectives: This study focused on PTEN and Livin expression and associations with malignancy in humanrenal clear cell carcinomas (RCCC). Methods: PTEN and Livin expression was assessed in 100 RCCC ...

The aim of this study was to elucidate the role of the integrin-linked kinase (ILK) gene in development ofhuman bladder transitional cell carcinoma (BTCC). Expression of ILK protein and ILK mRNA in 56 cases ofhuman BTCC ...

Aim: To study the causes and significance of both microscopic and macroscopic haematuria in adult patientsand assess possible relevance to early detection of urological cancers. Methods: 417 patients presenting ...

Background: Bisphenol A (BPA), an endocrine disrupting chemical, has been suspected to posecarcinogenic risks. However, likely mechanisms are obscure and there are difficulties to estimating its realsignificance for ...

Background: Little is known about interest in faith-based health promotion programs among Asian Americanpopulations. Among the Christian denominations, the Seventh-day Adventist (SDA) church is known to place astrong ...

Introduction: Fumonisin B1 (FB1) is a toxic and carcinogenic mycotoxin produced in cereals due to fungalinfection. This study was conducted to determine FB1 contamination of rice and corn samples and its ...

The purpose of this study was to examine the effect of a Toll-like receptor 5 (TLR5) agonist, CBLB502, onthe growth and radiosensitivity of A549 lung cancer cells in vivo. Expression of myeloid differentiation factor88 ...

The current study was performed to assess any association between the methylenetetrahydrofolate reductase(MTHFR) C677T polymorphism and risk of lung cancer in Henan province. This case-control study involved94patients with ...

Aims: We conducted a case-control study in a Chinese population to clarify the association betweenpolymorphisms in ERCC1 and XPD and susceptibility and survival of glioma. Methods: A total of 393 cases and410 ...

Background: This cross-sectional observational study was undertaken to identify the epidemiologicalcharacteristics of patients with gynecological malignancies in India, in relation to gynecological cancer ...

Despite clinical advances in anticancer therapy, there is still a need for novel anticancer metabolites, withhigher efficacy and lesser side effects. Oroxylum indicum (L.) Vent. is a small tree of the Bignoniaceae familywhich ...

Annona muricata L (Annonaceae), commonly known as soursop has a long, rich history in herbal medicinewith a lengthy recorded indigenous use. It had also been found to be a promising new anti-tumor agent innumerous in vitro ...

Objectives: The aim of the present study was to explore mechanisms underlying the effects of down-regulatingß-catenin expression on esophageal carcinoma (EC) cells. Methods: Cell cycle distribution ...

Background: Matrix metalloproteinase-9 (MMP-9) is associated with disruption of basement membranesof blood vessels and promotion of metastasis through the lymphatics. However, its prognostic value for survivalin ...