Introduction: Cervical cancer is a leading cause of death in developing countries. However, taking regular Pap smearsscreening, one of the most effective screening tests, can reduce chance of cervical cancer remarkably. ...

There is increasing evidence that host genetic variations may influence the natural history of chronic hepatitis C virus(HCV) infection. The aim of this study was to determine the association between single nucleotide ...

Background: The incidence of breast cancer in Lebanon is higher than any other Middle –Eastern country, isdiagnosed at a younger age than women in Western countries, and is more aggressive and fatal. Therefore ...

Background: Burnout syndrome (BOS) is defined as a work-related psychological state characterized by emotionalexhaustion, depersonalization, and low sense of personal accomplishment. Despite the extensive data on ...

Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major toxicity that requires treatmentmodification or cessation and worsens patients' quality of life. Its incidence is 30–40%. Occurrence and severity ...

United Arab Emirates initiated the colorectal cancer (CRC) screening on 2013. Yet, one of the barriers to participationin CRC screening is lack of knowledge about the importance of CRC, its risk factors, and the ...

Background: The central giant cell granuloma (CGCG) is generally considered a non-neoplastic lesion. However,some cases show aggressive behavior like neoplasms. Based on clinical observations, a number of researchers ...

Objective: Tobacco-free policies in hospital campus reduce exposure to tobacco smoke; change the demeanour ofthe professionals, patients and people visiting hospitals towards tobacco use. Section-4, 5 and 6 of COTPA ...

Cytochromes P450s (CYPs) constitute a superfamily of enzymes that catalyze the metabolism of drugs and othersubstances. Endogenous substrates of CYPs include eicosanoids, estradiol, arachidonic acids, cholesterol, ...

Background: CPUK02 (15-Oxosteviol benzyl ester) is a new ent-kaurenoid derivative of stevioside and exhibitsstrong anti-cancer activity. Nowadays, the pattern of epigenetic in cancer has been topic of many studies ...

Objective: Homo- and heterodimerization of the receptor tyrosine kinase HER2 hyperactivate several downstreamsignaling pathways, leading to uncontrolled growth and proliferation of tumor cells. Anti-HER2 monoclonal ...

Objective: Glucocorticoids are one of the most important drugs in the treatment of acute lymphoblastic leukemiafor children. It is very important to response to glucocorticoid in the prognosis of these patients. ...

Background: MicroRNAs (miRNAs) play important roles in the pathogenesis of leukemia and their alteredexpression is associated with many types of solid and hematological malignancies. Methods: The study was performed

Background: Germline and somatic polymorphisms and mutations of the Androgen Receptor (AR) gene are known tobe associated with the incidence of prostate cancer (PCa) in different populations. In this study we assessed ...

Objective: This study was designed to describe the course of IgG/IgA responses in cervical secretions and in serumone year after the first dose of intramuscular administration of the HPV16/18 AS04-adjuvant vaccine. ...

Background: Epithelial growth factor receptor tyrosine kinase inhibitor (EGFR TKI) revolutionize the standardof care for advanced non-small cell lung cancer (NSCLC) harboring sensitive EGFR mutation. Liver toxicity ...

Background: Colorectal cancer (CRC) is second in incidence rates in both genders in the Kingdom of Bahrain,with the number of new CRC cases sharply increasing in the last two decades. This study aimed to assess the ...

Background: Late diagnosis and improper treatment lead to many avoidable deaths in patients suffering from oralcancer. This study evaluated the knowledge and perceptions of general dentists regarding oral precancerous ...

Organogenesis and tumorigenesis seem to be followinga set pretty similar instructions and pathways and tumors,like any other organ, can be seen as the summation ofmany different cell types. However, unlike ...

Objective: Although several factors have been shown to have etiological roles in colorectal cancer, few investigationshave addressed how and to what extent these factors affect the genetics and pathology of the ...