Introduction: Cervical cancer is a leading cause of death in developing countries. However, taking regular Pap smearsscreening, one of the most effective screening tests, can reduce chance of cervical cancer remarkably. ...

Purpose: Breast cancer can be cured if diagnosed early, with digital mammography which is one of the mosteffective imaging modalities for early detection. However mammogram images often come with low contrast, high

Background: Burnout syndrome (BOS) is defined as a work-related psychological state characterized by emotionalexhaustion, depersonalization, and low sense of personal accomplishment. Despite the extensive data on ...

Objective: This study aimed to understand the effects of the use of oral contraceptive to breast cancer risk in sixreferral hospitals in Indonesia. Methods: The research design was hospital based case-control, conducted ...

Background: Germline and somatic polymorphisms and mutations of the Androgen Receptor (AR) gene are known tobe associated with the incidence of prostate cancer (PCa) in different populations. In this study we assessed ...

Background: CPUK02 (15-Oxosteviol benzyl ester) is a new ent-kaurenoid derivative of stevioside and exhibitsstrong anti-cancer activity. Nowadays, the pattern of epigenetic in cancer has been topic of many studies ...

Objective: Tobacco-free policies in hospital campus reduce exposure to tobacco smoke; change the demeanour ofthe professionals, patients and people visiting hospitals towards tobacco use. Section-4, 5 and 6 of COTPA ...

Objective: Glucocorticoids are one of the most important drugs in the treatment of acute lymphoblastic leukemiafor children. It is very important to response to glucocorticoid in the prognosis of these patients. ...

Objective: Homo- and heterodimerization of the receptor tyrosine kinase HER2 hyperactivate several downstreamsignaling pathways, leading to uncontrolled growth and proliferation of tumor cells. Anti-HER2 monoclonal ...

There is increasing evidence that host genetic variations may influence the natural history of chronic hepatitis C virus(HCV) infection. The aim of this study was to determine the association between single nucleotide ...

Objective: Globally oral cancer is one of the ten most common cancers with prevalence being high in Centraland South East Asian countries. This survey was conducted to estimate the prevalence of oral pre-malignant ...

Objective: A long persistent of Chronic Hepatitis B (CHB) infection may develop liver cirrhosis or hepatocellularcarcinoma (HCC) and about one million people die due to HBV -related liver cancer and end-stage liver ...

Background: Epithelial growth factor receptor tyrosine kinase inhibitor (EGFR TKI) revolutionize the standardof care for advanced non-small cell lung cancer (NSCLC) harboring sensitive EGFR mutation. Liver toxicity ...

Background: Endometrial carcinomas are common gynecologic malignancies worldwide. In Egypt they represent2.6 %. We evaluated the role of morphometry and MMP-9 immunohistochemical expression to differentiate atypical

Cytochromes P450s (CYPs) constitute a superfamily of enzymes that catalyze the metabolism of drugs and othersubstances. Endogenous substrates of CYPs include eicosanoids, estradiol, arachidonic acids, cholesterol, ...

Objective: Small non-coding RNA molecules are dysregulated in prostate cancer (PCa). In our previous study,downregulation of miR-1266 and miR-185 was demonstrated in PCa tissues and cell lines. The aim of the present

Objective:According to current guidelines, there is no clear second-line treatment for advanced liver cancer.In practice, clinicians have attempted to use thalidomide(TLD) combined with transcatheter arterial ...

Background: MicroRNAs (miRNAs) play important roles in the pathogenesis of leukemia and their alteredexpression is associated with many types of solid and hematological malignancies. Methods: The study was performed

Introduction: Stigma is one of the psychosocial and intercultural issues that can be found in chronic diseases,including cancer. Stigma may reduce communication due to social isolation, feeling shame and others' ...

The evidence that prostate cancer is associated to physical inactivity is inconsistent. We studied the association ofperceived physical workload (PPWL) at work and incidence of prostate cancer in a case-control ...