Advanced Imaging Applications for Locally Advanced Cervical Cancer

Abstract

Advanced imaging approaches (computed tomography, CT; magnetic resonance imaging, MRI;18F-fluorodeoxyglucose positron emission tomography, FDG PET) have increased roles in cervical cancer stagingand management. The recent FIGO (International Federation of Gynecology and Obstetrics) recommendationsencouraged applications to assess the clinical extension of tumors rather than relying on clinical examinationsand traditional non-cross sectional investigations. MRI appears to be better than CT for primary tumors andadjacent soft tissue involvement in the pelvis. FDG-PET/CT has increased in usage with a particular benefitfor whole body evaluation of tumor metabolic activity. The potential benefits of advanced imaging are assistingselection of treatment based upon actual disease extent, to adequately treat a tumor with minimal normal tissuecomplications, and to predict the treatment outcomes. Furthermore, sophisticated external radiation treatmentand brachytherapy absolutely require advanced imaging for target localization and radiation dose calculation.