مرور Volume 22, Issue 11 بر اساس عنوان
در حال نمایش موارد 1 - 12 از 12
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Akt inhibitor deguelin aggravates inflammation and fibrosis in myocarditis
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): Myocarditis is characterized by inflammatory cell infiltration in myocardial stroma. Attenuation of tumor necrosis factor (TNF)-α and interleukin (IL)-1β is a reliable mark for ...
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Association of lipid markers with coronary heart disease and stroke mortality: A 15-year follow-up study
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): It has been proposed that lipid markers may predict cardiovascular events; however, their effect may vary depending on the type of cardiovascular disease. The purpose of this study ...
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Conditioned medium obtained from human amniotic membrane-derived mesenchymal stem cell attenuates heart failure injury in rats
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): Heart failure (HF) is one of the leading causes of death worldwide. Due to beneficial effects of stem cells, paracrine secretion of them has recently been used by researchers. The ...
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Contribution of potassium channels, beta2-adrenergic and histamine H1 receptors in the relaxant effect of baicalein on rat tracheal smooth muscle
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): Baicalein, a compound extracted from a variety of herbs, showed various pharmacological effects. This study evaluated the relaxant effects of baicalein and its underlying molecular ...
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Eupafolin ameliorates lipopolysaccharide-induced cardiomyocyte autophagy via PI3K/AKT/mTOR signaling pathway
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): Eupafolin, a major active component of Eupatorium perfoliatum L., has anti-inflammatory and anti-oxidant properties. Lipopolysaccharide (LPS) is responsible for myocardial depression. ...
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The genus <i>Cuscuta</i> (Convolvolaceac): An updated review on indigenous uses, phytochemistry, and pharmacology
(Mashhad University of Medical Sciences, 2019-11-01)Cuscuta, commonly known as dodder, is a genus of family convolvolaceace. Approximately 170 species of Cuscuta are extensively distributed in temperate and subtropical areas of the world. Species of this genus are widely ...
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Metabolomics approach reveals urine biomarkers and pathways associated with the pathogenesis of lupus nephritis
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): lupus nephritis (LN) is a severe form of systemic lupus erythematosus (SLE) with renal complications. Current diagnosis is based on invasive renal biopsy and serum antibodies and ...
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Potential therapeutic effect of Moroccan propolis in hyperglycemia, dyslipidemia, and hepatorenal dysfunction in diabetic rats
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): The effect of propolis collected in Morocco on blood glucose, lipid profile, liver enzymes, and kidney function was investigated in control and diabetic rats. Materials ...
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The prevalence of exotoxins, adhesion, and biofilm-related genes in <i>Staphylococcus aureus</i> isolates from the main burn center of Tehran, Iran
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): The present study investigated the prevalence of genes encoding for exotoxins, adhesion and biofilm factors in Staphylococcus aureus isolates obtained from samples in a referral burn ...
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Protection of BALB/c mice against pathogenic <i>Brucella abortus</i> and <i>Brucella melitensis</i> by vaccination with recombinant Omp16
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): Prevention of the globally spread zoonotic infection, brucellosis which affects an extensive range of hosts is still challenging researchers. There are no approved vaccines for the ...
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Reactive oxygen species mediate TNF-α-induced inflammatory response in bone marrow mesenchymal cells
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): It is generally believed that the inflammatory response in bone marrow mesenchymal stem cells (BMSCs) transplantation leads to poor survival and unsatisfactory effects, and is mainly ...
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Renal histopathological and biochemical changes following adjuvant intervention of <i>Momordica charantia</i> and antiretroviral therapy in diabetic rats
(Mashhad University of Medical Sciences, 2019-11-01)Objective(s): Diabetic nephropathy (DN) is an important primary cause of end-stage kidney disease. This study explores the mechanisms of the reno-protective effects of Momordica charantia (M. ...
