مرور Volume 19, Issue 9 بر اساس عنوان
در حال نمایش موارد 1 - 11 از 11
-
Anti-inflammatory effect of Yu-Ping-Feng-San via TGF-β1 signaling suppression in rat model of COPD
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): Yu-Ping-Feng-San (YPFS) is a classical traditional Chinese medicine that is widely used for treatment of the diseases in respiratory systems, including chronic obstructive pulmonary ...
-
Apoptosis induction of human endometriotic epithelial and stromal cells by noscapine
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): Endometriosis is a complex gynecologic disease with unknown etiology. Noscapine has been introduced as a cancer cell suppressor. Endometriosis was considered as a cancer like disorder, ...
-
Association of morphine-induced analgesic tolerance with changes in gene expression of GluN1 and MOR1 in rat spinal cord and midbrain
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): We aimed to examine association of gene expression of MOR1 and GluN1 at mRNA level in the lumbosacral cord and midbrain with morphine tolerance in male Wistar rats.
-
The effect of oral and intraurethral trimetazidine use on urethral healing
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): We aimed to study the effect of trimetazidine (TMZ) on urethral wound repair. Materials and Methods: A total of 52 male rats were used; 8 groups were formed: ...
-
The Expression implication of GDNF in ventral horn and associated remote cortex in rhesus monkeys with hemisected spinal cord injury
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): Glial cell line-derived neurotrophic factor (GDNF) can effectively promote axonal regeneration，limit axonal retraction，and produce a statistically significant improvement in motor ...
-
Fluvoxamine inhibits some inflammatory genes expression in LPS/stimulated human endothelial cells, U937 macrophages, and carrageenan-induced paw edema in rat
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): Fluvoxamine is a well-known selective serotonin reuptake inhibitor (SSRI); Despite its anti-inflammatory effect, little is known about the precise mechanisms involved. In our previous ...
-
Immunomodulatory activities of gemifloxacin in mice
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s):Gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. In this study, an attempt was made to evaluate the immunomodulatory ...
-
Potentiation of human papilloma vaccine candidate using naloxone/alum mixture as an adjuvant: increasing immunogenicity of HPV-16E7d vaccine
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): Many types of human papillomaviruses (HPVs) have been identified, with some leading to cancer and others to skin lesions such as anogenital warts. Studies have demonstrated an ...
-
Prednison provokes serum and vasoactive substances in a mice model of immune thrombocytopenia
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): The main objective of this study was to investigate the variations of β-endorphin (β-EP), vasoactive intestinal peptide (VIP), serotonin (5-HT) and norepinephrine (NE) of immune ...
-
Protective effect of silymarin against chemical-induced cardiotoxicity
(Mashhad University of Medical Sciences, 2016-09-01)Cardiac disorders remain one of the most important causes of death in the world. Oxidative stress has been suggested as one of the molecular mechanisms involved in drug-induced cardiac toxicity. Recently, several natural ...
-
Total flavonoid extract from Coreopsis tinctoria Nutt. protects rats against myocardial ischemia/reperfusion injury
(Mashhad University of Medical Sciences, 2016-09-01)Objective(s): This study aimed to evaluate the protective effects of total flavonoid extract from Coreopsis tinctoria Nutt.(CTF)against myocardial ischemia/reperfusion injury (MIRI) using ...
