Volume 19, Issue 5
مرور بر اساس
ارسال های اخیر
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Enhanced expression of transient receptor potential channel 3 in uterine smooth muscle tissues of lipopolysaccharide-induced preterm delivery mice
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): We aimed to investigate the influence of transient receptor potential channel 3 (TRPC3) on lipopolysaccharide-induced (LPS) preterm delivery mice. Materials and ...
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Breviscapine prevents downregulation of renal water and sodium transport proteins in response to unilateral ureteral obstruction
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s):Our recent report indicates that breviscapine play a protective role of the kidney by down-regulating transforming growth factor-β1(TGF-β1), α-smooth muscle actin (α-SMA) and alleviating ...
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Evaluation, prediction and optimization the ultrasound-assisted extraction method using response surface methodology: antioxidant and biological properties of Stachys parviflora L.
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s):To optimize the extraction method using response surface methodology, extract the phenolic compounds, and identify the antioxidant and biological properties of Stachys parviflora L. ...
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Alpha-tocopherol ameliorates experimental autoimmune encephalomyelitis through the regulation of Th1 cells
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): Multiple sclerosis (MS) is a serious neurological autoimmune disease, it commonly affects young adults. Vitamin E (Vit E) is an important component of human diet with antioxidant ...
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Design of eudragit RL nanoparticles by nanoemulsion method as carriers for ophthalmic drug delivery of ketotifen fumarate
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): Ketotifen fumarate (KF) is a selective and noncompetitive histamine antagonist (H1-receptor) that is used topically in the treatment of allergic conditions of rhinitis and conjunctivitis. ...
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Administration of orexin receptor 1 antagonist into the rostral ventromedial medulla increased swim stress-induced antinociception in rat
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): Intracerebroventricular injection of orexin-A (hypocretin-1) antagonist has been shown to inhibit stress-induced analgesia. However the locations of central sites that may mediate ...
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Difference in transient ischemia-induced neuronal damage and glucose transporter-1 immunoreactivity in the hippocampus between adult and young gerbils
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): The alteration of glucose transporters is closely related with the pathogenesis of brain edema. We compared neuronal damage/death in the hippocampus between adult and young gerbils ...
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The protective effects of epigallocatechin gallate on lipopolysa ccharide-induced hepatotoxicity: an in vitro study on Hep3B cells
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): In the present study, our aim was to investigate the possible protective effects of epigallocatechin gallate (EGCG) on lipopolysaccharide (LPS)-induced hepatotoxicity by using Hep3B ...
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Effect of WR-1065 on 6-hydroxydopamine-induced catalepsy and IL-6 level in rats
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): Neuroinflammation and oxidative stress play a key role in pathogenesis of Parkinson's disease (PD). In the present study we investigated the effect of reactive oxygen species (ROS) ...
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Protective effects of fractions from Artemisia biennis hydro-ethanolic extract against doxorubicin-induced oxidative stress and apoptosis in PC12 cells
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): This study was designed to indicate whether different fractions from Artemisia biennis hydroethanolic extract could provide cytoprotection against oxidative stress ...
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Feature selection using genetic algorithm for breast cancer diagnosis: experiment on three different datasets
(Mashhad University of Medical Sciences, 2016-05-01)Objective(s): This study addresses feature selection for breast cancer diagnosis. The present process uses a wrapper approach using GA-based on feature selection and PS-classifier. The results of ...
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Therapeutic effects of saffron (Crocus sativus L.) in digestive disorders: a review
(Mashhad University of Medical Sciences, 2016-05-01)Saffron, the dried red-orange stigmas of Crocus sativus L, has been known as a flavoring agent, food coloring and traditional herbal medicine. Pharmacological effects of saffron are mainly attributed to crocin, ...
