مرور Volume 21, Issue 2 بر اساس موضوع "Drug resistance"

در حال نمایش موارد 1 - 1 از 1

CRISPR/Cas9, a new approach to successful knockdown of ABCB1/P-glycoprotein and reversal of chemosensitivity in human epithelial ovarian cancer cell line

Norouzi-Barough, Leyla؛ Sarookhani, Mohammad reza؛ Salehi, Rasoul؛ Sharifi, Mohammadreza؛ Moghbelinejad, Sahar (Mashhad University of Medical Sciences, 2018-02-01)

Objective(s): Multidrug resistance (MDR) is a major obstacle in the successful chemotherapy of ovarian cancer. Inhibition of P-glycoprotein (P-gp), a member of ATP-binding cassette (ABC) transporters, ...