مرور Volume 14, Issue 3 بر اساس تاریخ انتشار

  • Human Leukocyte Antigen Class I and II Variants in Yemeni Patients with Chronic Renal Failure 

    Nassar, Mogahid Yahi'a؛ Al-Shamahy, Hassan Abdulwahab؛ Al-Samawi, Abdullah Saleh؛ Abu Asba, Nagieb Waza'a؛ El-Nono, Ibrahiem Husain؛ Masood, Haitham Abdulwahab (Shiraz Institute for Cancer Research, 2017-09-01)
    Background: Human leukocyte antigens (HLAs) are found to be significant genetic factors concerning the susceptibility of an individual to certain diseases. Objective: To determine the ...

  • Polyclonal Antibody against Different Extracellular Subdomains of HER2 Induces Tumor Growth Inhibition in vitro 

    Hosseini-Ghatar, Reza؛ Soltantoyeh, Tahereh؛ Bahadori, Motahareh؛ Khoshnoodi, Jalal؛ Golsaz-Shirazi, Forough؛ Jeddi-Tehrani, Mahmood؛ Amiri, Mohammad Mehdi؛ Shokri, Fazel (Shiraz Institute for Cancer Research, 2017-09-01)
    Background: Human epidermal growth factor receptor 2 (HER2) has a crucial role in several malignancies. The extracellular domain of HER2 (HER2-ECD) has been extensively employed as an important target in ...

  • Rapamycin Inhibits Expansion of Cord Blood Derived NK and T Cell 

    Zare, Monireh؛ Valipour, Behnaz؛ Mohammadi, Seyede Momeneh؛ Nouri, Mohammad؛ Movassaghpour, Aliakbar؛ Nozad Charoudeh, Hojjatollah (Shiraz Institute for Cancer Research, 2017-09-01)
    Background: The mammalian target of rapamycin (mTOR) is important in hematopoiesis. Despite the central role of mTOR in regulating the differentiation of immune cells, the effect of mTOR function on cord ...

  • Association of Human Leukocyte Antigens Class I & II with Graves’ Disease in Iranian Population 

    Mehraji, Zahra؛ Farazmand, Ali؛ Esteghamati, Alireza؛ Noshad, Sina؛ Sadr, Maryam؛ Amirzargar, Somayeh؛ Yekaninejad, Mir Saeed؛ Amirzargar, Aliakbar (Shiraz Institute for Cancer Research, 2017-09-01)
    Background: Graves' disease (GD), a highly rampant autoimmune disorder of the thyroid gland, is responsible for 60-80% of the clinical cases of hyperthyroidism. Over the past decades, genetic association ...

  • Reduced IFN-γ Production in Chronic Brucellosis Patients 

    Ghaznavi-Rad, Ehsanollah؛ Khosravi, Khadijeh؛ Zarinfar, Nader؛ Mosayebi, Ghasem (Shiraz Institute for Cancer Research, 2017-09-01)
    Background: Brucella is a well-known intracellular bacterium entailing acute and chronic illnesses in humans and domestic animals. The infection chronicity may be affected by the cell-mediated immunity and ...

  • Combination of Myelin Basic Protein Gene Polymorphisms with HLA-DRB1*1501 in Iranian Patients with Multiple Sclerosis 

    Nejati, Parham؛ Attar, Marzieh؛ Rahimian, Maryam؛ Fathi, Davood؛ Shahbazi, Majid (Shiraz Institute for Cancer Research, 2017-09-01)
    Background: Multiple sclerosis (MS), as a multifactorial autoimmune disease with complex genetic basis, causes demyelination in the central nervous system via cytokine responses to myelin antigens. Myelin ...