مرور Volume 15, Issue 2 بر اساس تاریخ انتشار

در حال نمایش موارد 1 - 6 از 6

  • Anti-inflammatory Effects of PMX205 in Mouse Macrophage Periodontitis Model 

    Li, Gege؛ Pan, Jiahui؛ Tang, Qiuling؛ Liu, Xinchan؛ Wang, Liuran؛ Meng, Yang؛ Yu, Weixian (Shiraz Institute for Cancer Research, 2018-06-01)
    Background: C5areceptor antagonistPMX205 is a synthetic hexapeptidecapable of blocking C5a-C5a receptor (C5aR) axis by simulating C5a active C-terminal amino acid residues. This hexapeptide presents good ...

  • The Relationship between Plasma Levels of Interleukin-6, Multiple Organ Dysfunction and Mortality in Orthopedic Patients 

    ebrahimpour, adel؛ Mirbolook, Ahamadreza؛ okhovatpour, mohammadali؛ sajadi, mohammadreza؛ makvandi, kamyar؛ mousavi, mohamad sadegh؛ saghari, sepehr؛ sadighi, mehrdad (Shiraz Institute for Cancer Research, 2018-06-01)
    Background: Interleukin 6 (IL-6) functions as both a pro-inflammatory cytokine and an anti-inflammatory cytokine. Objective: To evaluate the levels of IL-6 in patients with multiple organ ...

  • HLA Class I and Class II Genes Distribution of the Sistanis in Iran 

    aminikhah, mahdi؛ Yekaninejad, Mir Saeed؛ Nicknam, M.Hosein؛ Khosravi, Farideh؛ naroei nejad, Mehrnaz؛ Ansaripour, Bita؛ moradi, batol؛ Nikbin, Behrouz؛ Amirzargar, Aliakbar (Shiraz Institute for Cancer Research, 2018-06-01)
    Background: The high polymorphism in the human leukocyte antigen (HLA) genes can be used as an identity of individuals to compare with other populations. This extreme polymorphism in the HLA system is ...

  • Vaccination with Live Attenuated L. Major and TLR4 Agonist Promotes a Th1 Immune Response and Induces Protection against L. Major Infection in BALB/c Mice 

    Noorpisheh Ghadimi, Shamsi؛ Farjadian, Shirin؛ Hatam, Gholam Reza؛ Kalani, Mehdi؛ Sarkari, Bahador (Shiraz Institute for Cancer Research, 2018-06-01)
    Background: Toll like receptors play a major role in immune responses against Leishmania parasites. Objective: To evaluate the efficacy of vaccination with live attenuated L. ...

  • Hemin Induces the Activation of NLRP3 Inflammasome in N9 Microglial Cells 

    Tan, Yan؛ Tan, Si-Wei؛ Fan, Bo-Ya؛ Li, Lei؛ Zhou, Yuan-Guo (Shiraz Institute for Cancer Research, 2018-06-01)
    Background: Hemin is an important sterile component that induces a neuroinflammatory response after intracerebral hemorrhage, in which NLRP3 inflammasome activation has also proved to be ...

  • Increased Levels of AIM2 and Circulating Mitochondrial DNA in Type 2 Diabetes 

    Cataño Cañizalez, Yolanda؛ Uresti Rivera, Edith؛ Garcia Jacobo, Rocio؛ Portales Perez, Diana؛ Bastian, Yadira؛ Rodriguez Rivera, J؛ Gonzalez Amaro, Roberto؛ Enciso Moreno, Jose؛ Garcia Hernandez, Mariana (Shiraz Institute for Cancer Research, 2018-06-01)
    Background: Chronic inflammation has critical role in Type 2 diabetes (T2D), in which IL-1β contributes in insulin resistance and beta cell dysfunction. The activation of NLRP3 and AIM2 by endogens ligands, ...