Hospital-based Study of Endometrial Cancer Survival inMumbai, India

Abstract

<b>Background:</b> Endometrial cancer is common in western women, and the rates are very high; however inIndia, the rates are as low as 4.3 per 100,000 (Delhi). <br/><b>Objective</b>: To estimate the survival of endometrial cancerpatients based on age, education, family history, tobacco habit, number of pregnancies, clinical extent of diseaseand treatment received. Materials and <br/><b>Methods</b>: The present retrospective study was carried out at the TataMemorial Hospital (TMH), Mumbai, India, between 1999-2002. 310 cases treated in TMH were considered aseligible entrants for the study. Five-year survival rates were estimated using actuarial and loss-adjusted (LAR)methods. <br/><b>Results</b>: The proportions of patients dying above 50 years of age, non-residents and illiterates washigher than their counterparts. 54.8% of patients had some form of treatment before attending TMH. Therewere only 4.2% tobacco-chewers and only 6.1% had a family history of cancer. There were 25.8% who had3-5 pregnancies (not living children) and 38.1% did not remember the pregnancy history. The 5-year overallsurvival rate was 92%. The five-year rates indicated better prognosis for those aged less than 50 years (97%),non-tobacco-chewers (94%), with no family history of cancer (93%), with localized disease (93%) and thosetreated with surgery either alone or as a combination treatment (95%). <br/><b>Conclusions</b>: The present study showedthat endometrial cancer patients with localized disease at diagnosis have a good outcome in India. A detailedstudy will help in understanding the prognostic indicators for survival especially with the newer treatmenttechnologies now available.