The cellular apoptosis susceptibility (CSE1L) gene has been demonstrated to regulate multiple cellularmechanisms including the mitotic spindle check point as well as proliferation and apoptosis. However, theimportance of ...

The aim of this study was to investigate the diagnostic value of superoxide dismutase (SOD) in tuberculouspleural effusions (TPEs) and malignant pleural effusions (MPEs). Pleural effusion (PE) samples from 100 patientswere ...

Background: Palliative chemotherapy with cisplatin/5-fluorouracil (5FU) is the commonest regimen employedfor metastatic and recurrent head and neck squamous cell carcinoma (SCCHN) and nasopharyngeal carcinoma(NPC). ...

Background: Peritoneal washing cytology (PWC) that shows the microscopic intra-peritoneal spread ofgynaecologic cancers is not used in staging but is known as prognostic factor and effective in planning theintensity ...

Background: Colorectal cancer has several modifiable behavioural risk factors but their relationship tothe risk of colon and rectum cancer separately and between countries with high and low incidence is not ...

Background: Colorectal cancer (CRC) exists in a more common sporadic form and less common hereditaryforms, associated with the Lynch syndrome, familial adenomatous polyposis (FAP) and other rare syndromes.Sporadic ...

Background: In India, tobacco consumption is responsible for one of the highest rates of oral cancer inthe world, the annual oral cancer incidence is steadily increasing among young tobacco users. Studies havedocumented ...

Background: Endometrial cancer is common in western women, and the rates are very high; however inIndia, the rates are as low as 4.3 per 100,000 (Delhi). Objective: To estimate the survival of endometrial ...

Cervical cancer is the most important female gynecological cancer, the second leading cause of cancer mortalityin women worldwide and the second most common cancer in Thai women. The major cause of cervical cancer ispersistent ...

Ku70/80 heterodimer is a central element in the nonhomologous end joining (NHEJ) DNA repair pathway,Ku80 playing a key role in regulating the multiple functions of Ku proteins. It has been found that the Ku80 proteinlocated ...

Objective: To investigate the expression of Twist and E-cadherin in ovarian cancer tissues as well as the roleof epithelial-mesenchymal transformation (EMT) in ovarian cancer metastasis. Method: The ...

Introduction: Capture-recapture methods have been suggested for reducing costs of disease registration as wellas reducing bias in incidence estimations. This study aimed to estimate the gastric cancer incidence ...

Background: Breast cancer is worldwide the most common cancer in women and is a major public healthproblem. Genes with high or low penetrance are now clearly implicated in the onset of breast cancer, mostlythe BRCA ...

Background: Prognostication of breast cancer using clinico-pathologic variables, although useful, remainsimperfect. Recent research has focused on finding new markers of prognosis using gene expression profiling.Panels ...

Cancer is a highly complex medical problem with ramifications for public health throughout the world. Moststudies have mainly focused on change in the nuclei as being aetiologically responsible. Few have examined therelationship ...

Our aim was to test the hypothesis that preoperative serum levels of matrix metalloproteinase-7 (MMP-7)and -9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) levels correlate with pathologicalfeatures. ...

Background: In normal cells, activated epidermal growth factor receptor (EGFR) molecules are subjected toubiquitination-mediated proteasome degradation pathway by c-Cbl, an ubiquitin ligase that checks uncontrolle ...

Objective: To evaluate the relationships between lymph node ratio (LNR, the ratio of positive lymph nodesin excised axillary lymph nodes) and disease-free survival (DFS) by comparing with traditional absolute ...

Although there have been many studies investigating possible associations between the C1653T mutation andrisk of HCC, the results have been inconsistent. We conducted searches of the published literature in Pubmedand Embase ...

Background: The present study was designed to comparatively assess alteration of biochemical parameters inbile duct cancer and gall stone disease. Materials and Methods: A hospital based case-control ...