• Preparation, Characterization and Evaluation of Drug Release Properties of Simvastatin-loaded PLGA Microspheres 

  Masaeli, Reza؛ Jafarzadeh Kashi, Teherh Sadat؛ Dinarvand, Rassoul؛ Tahriri, Mohammadreza؛ Rakhshan, Vahid؛ esfandyari-manesh, mehdi (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Microspheres formulated from poly (D,L-lactic-co-glycolide) (PLGA), a biodegradable polymer, have been extensively evaluated as a drug delivery system. In this study, the preparation, characterization and drug release ...

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• Ethanol and Cancer Induce Similar Changes on Protein Expression Pattern of Human Fibroblast Cell 

  zamanian azodi, mona؛ Rezaei Tavirani, Mostafa؛ Rahmati-Rad, Sara؛ Rezaie-Tavirani, Mostafa (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Abstract Ethanol has a vast consumption around the world. Many researches confirmed some adverse effect of this component on human health. In addition, recent studies showed significant alteration in both cellular population, ...

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• Mitochondrial apoptosis induced by Chamaemelum nobile extract in breast cancer cells 

  Mostafapour Kandelous, Hirsa؛ Salimi, Misha؛ Khuri, Vahid؛ Rastkari, Noushin؛ Amanzadeh, Amir؛ Salimi, Mona (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Chamaemelum nobile (Asteraceae) commonly known as 'Roman chamomile' is a medicinal plant used for numerous diseases in traditional medicine, although its anticancer activity is unknown. The present study was carried out ...

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• Determination of Benzo[a]pyrene in Traditional, Industrial and Semiindustrial Breads Using a Modified QuEChERS Extraction, Dispersive SPE and GC-MS and Estimation of its Dietary Intake. 

  Esalmizad, samira؛ Kobarfard, Farzad؛ Javidnia, Katayoun؛ Sadeghi, Ramezan؛ Bayat, Mitra؛ Shahanipour, Sara؛ Khalighian, Najmeh؛ Yazdanpanah, Hassan (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  A fast and simple modified QuEChERS extraction method was developed for determination of Benzo[a]pyrene (BaP) in 137 traditional (Sangak), semi-industrial (Sangak) and industrial bread samples using spiked calibration ...

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• A Wound Healing Formulation Based on Iranian Traditional Medicine and Its HPTLC Fingerprint 

  Jahandideh, Maryam؛ Hajimehdipoor, Homa؛ Mortazavi, Seyed alireza؛ dehpour, Ahmadreza؛ Hassanzadeh, Gholamreza (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  The present study reports formulation of a traditionally used poly herbal product for wound healing and its chromatographic analysis by HPTLC. Herbal therapy was the common treatment prescribed by Iranian physicians for ...

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• Anticancer Activity a of Caspian Cobra (Naja naja oxiana) snake Venom in Human Cancer Cell Lines Via Induction of Apoptosis 

  ebrahim, karim؛ Vatanpour, Hossein؛ Mirakabadi, Abbas؛ Hosseini Shirazi, Farshad؛ Nakhjavani, Maryam (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Abstract Cancer is the leading cause of death worldwide. Current anticancer drugs involve various toxic side effects; efforts are ongoing to develop new anticancer agents especially from the screening of natural compounds. ...

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• Fragment-Based Hologram QSAR Studies on a Series of 2,4-Dioxopyrimidine-1-Carboxamides As Highly Potent Inhibitors of Acid Ceramidase 

  Yang, Xianglin؛ Zhou, Yuan؛ Liu, Xin-Ling (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  A series of structurally related 2,4-dioxopyrimidine-1-carboxamide derivatives as highly potent inhibitors against acid ceramidase were subjected to hologram quantitative structure-activity relationship (HQSAR) analysis. ...

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• Anti-inflammatory Effect of Amitriptyline on Ulcerative Colitis in Normal and Reserpine-Induced Depressed Rats 

  Fattahian, Ehsan؛ Hajhashemi, Valiollah؛ Rabbani, Mohammad؛ Minaiyan, Mohsen؛ Mahzouni, Parvin (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Depressive disorders are more common among persons with chronic diseases such as inflammatory bowel disease and anti-inflammatory effect of some antidepressants such as amitriptyline has been reported. Acetic acid colitis ...

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• Oral Ciprofloxacin Prophylaxis in Patients Undergoing High Dose Therapy and Autologous Hematopoietic Stem Cell Transplantation 

  Tabarraee, Mahdi؛ Tavakoli-Ardakani, Maria؛ mehdizadeh, mahshid؛ ghadiany, mojtaba؛ rezvani, hamid؛ Hajifathali, Abbas؛ Khamsi, samiyeh (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Background: Antibiotic prophylaxis is usually used in allogenic stem cell transplantation, but its use in Autologous Stem Cell Transplantation (ASCT) is controversial. We evaluated the efficacy of ciprofloxacin prophylaxis ...

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• Detecting Diseases in Medical Prescriptions Using Data Mining Tools and Combining Techniques 

  Teimouri, Mehdi؛ Farzadfar, Farshad؛ soudi alamdari, mahsa؛ Hashemi Meshkini, Amir؛ Adibi Alamdari, Parisa؛ Rezaei-Darzi, Ehsan؛ Varmaghani, Mehdi؛ zeynalabedini6, Aysan (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Data about the prevalence of communicable and non-communicable diseases, as one of the most important categories of epidemiological data, is used for interpreting health status of communities. This study aims to calculate ...

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• Synthesis of Some Spiro Indeno[1,2-b]pyrido[2,3-d]Pyrimidine-5,3′- Indolines as New Urease Inhibitors 

  Asadi, Shima؛ Mohammadi Ziarani, Ghodsi؛ Badiei, Alireza؛ Sharifi, Amirhossein؛ Amanlou, Massoud (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  New series of spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines as new urease inhibitors were synthesized by the catalytic procedure in high yield and short reaction time. In this method, biacidic carbon was prepared ...

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• Protective Effect of Crocin on Gastric Mucosal Lesions Induced by Ischemia-Reperfusion Injury in Rats 

  Mard, Seyyed Ali؛ Azad, Mojib؛ ahangarpour, akram (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  The present study aimed to evaluate the protective effect of crocin on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rats.Forty male rats were randomly divided into sham, control (I/R injury) and ...

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• Human Placental Extract Ameliorates Structural Lung Changes Iinduced by Amiodarone in Rats 

  Samiei, Fatemeh؛ Jamshidzadeh, Akram؛ Noorafshan, Ali؛ Ghaderi, Amir (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Amiodarone is used in treatment of cardiac arrhythmias. Therapeutic use of amiodarone is limited by its side effects, including pulmonary toxicity. Human Placenta Extract (HPE) contains a variety of bio-active substances. ...

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• Design and Optimization of a New Voltammetric Method for Determination of Isoniazid by Using PEDOT Modified Gold Electrode in Pharmaceuticals 

  Demirkaya-Miloglu, Fatma؛ Oznuluer, Tuba؛ Ozdurak, Buket؛ Miloglu, Elmas (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Isoniazid (INH) was studied with regard to its electrochemical treatment on a strongly alkaline solution of a poly (3,4-ethylenedioxythiophene)-modified gold electrode, using both cyclic voltammetry and controlled potential ...

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• The Effect of Protocatechuic Acid on Blood Pressure and Oxidative Stress in Glucocorticoid-induced Hypertension in Rat 

  Safaeian, Leila؛ Hajhashemi, Valiollah؛ Haghjooye Javanmard, Shaghayegh؛ Sanaye Naderi, Hamed (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Oxidative stress is one of the important mechanisms involved in Dexamethasone (Dex)-induced hypertension. Protocatechuic acid (PCA) is a natural compound with high antioxidant capacity. In this investigation, the effect ...

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• Triterpene Constituents of Euphorbia Erythradenia Bioss. and their Anti-HIV Activity 

  ayatollahi, seyed abdulmajid؛ Zarei, Seyed Mohammad؛ Memarnejadian, Arash؛ Ghanadian, Mustafa؛ Heydarian Moghadam, Mohammad؛ Kobarfard, Farzad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  Phytochemical investigation of the aerial parts of Euphorbia erythradenia Bioss. (Euphorbiaceae), one of Iranian endemic Euphorbias, with particular attention to triterpene constituents, using methanol solvent extraction ...

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• Small Molecules as Protein-ProteinInteraction Inhibitors 

  Hajimahdi, Zahra (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

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• Barriers to liposomal gene delivery: from application site to the target 

  Moghimi, Hamid Reza؛ Saffari, Mostafa؛ Dass, Crispin (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  AbstractGene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. One promising form of gene delivery system (DDS) is liposomes. The success of liposome-mediated ...

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• Synthesis and Antibacterial Activity of Novel Hydroxy Semicarbazone Derivatives 

  Hariri, Elham؛ Mahboubi, Arash؛ Rahmani, Parisa؛ Haj Mohammad Ebrahim Tehrani, Kamaleddin؛ Babaeian, Mohammad؛ Mashayekhi, Vida؛ Kobarfard, Farzad (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  A series of hydroxysemicarbazone derivatives of substituted diaryl ketones and acetophenones were synthesized and their structures were confirmed by analytical and spectroscopic methods including elemental analysis, infrared ...

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• In-vitro Studies on Calotropis procera Leaf Extracts as Inhibitors of Key Enzymes Linked to Diabetes Mellitus 

  Kazeem, Idowu؛ Mayaki, Ayuva؛ Ogungbe, Bimpe؛ Ojekale, Anthony (School of Pharmacy, Shahid Beheshti University of Medical Sciences, 2016-03-01)

  The side effects associated with the usage of synthetic antidiabetic drugs make it imperative to search for alternative drugs from medicinal plants. Therefore, this study was aimed at evaluating the α-amylase and α-glucosidase ...

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