Volume 15, Issue 9
مرور بر اساس
ارسال های اخیر
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Under-use of Radiotherapy in Stage III Bronchioaveolar Lung Cancer and Socio-economic Disparities in Cause Specific Survival: a Population Study
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: This study used the receiver operating characteristic curve (ROC) to analyze Surveillance,Epidemiology and End Results (SEER) bronchioaveolar carcinoma data to identify predictive models and potentialdisparity ...
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Association of the XRCC1 c.1178G>A Genetic Polymorphism with Lung Cancer Risk in Chinese
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)The X-ray repair cross-complementing group 1 protein (XRCC1) plays important roles in the DNA baseexcision repair pathway which may influence the development of lung cancer. This study aimed to evaluatethe potential ...
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Assessing Misdiagnosis of Relapse in Patients with Gastric Cancer in Iran Cancer Institute Based on a Hidden Markov Multi-state Model
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: Accurate assessment of disease progression requires proper understanding of natural diseaseprocess which is often hidden and unobservable. For this purpose, disease status should be clearly detected.But ...
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8-60hIPP5m-Induced G2/M Cell Cycle Arrest Involves Activation of ATM/p53/p21cip1/waf1 Pathways and Delayed Cyclin B1 Nuclear Translocation
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Protein phosphatase 1 (PP1) is a major serine/threonine phosphatase that controls gene expression andcell cycle progression. The active mutant IPP5 (8-60hIPP5m), the latest member of the inhibitory molecules forPP1, has ...
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Increased Argonaute 2 Expression in Gliomas and its Association with Tumor Progression and Poor Prognosis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: Previous studies have showed that argonaute 2 is a potential factor related to genesis of severalcancers, however, there have been no reports concerning gliomas. Methods: Paraffin specimens ...
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Significance of ABO-Rh Blood Groups in Response and Prognosis in Breast Cancer Patients Treated with Radiotherapy and Chemotherapy
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: To evaluate whether ABO-Rh blood groups have significance in the treatment response andprognosis in patients with non-metastatic breast cancer. Materials and Methods: We retrospectively ...
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Lack of Association Between CYP1A1 Polymorphisms and Risk of Bladder Cancer: a Meta-analysis
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: The effects of CYP1A1 gene polymorphisms on the risk of bladder cancer (BC) remaincontroversial. We carried out a meta-analysis to clarify the role of CYP1A1 gene polymorphisms in BC. Materialand ...
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Role of TGF-β1 in Human Colorectal Cancer and Effects after Cantharidinate Intervention
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Effects of transforming growth factor-beta (TGF-β) were investigated in human colorectal cancer, and theinfluence of cantharidinate in inhibiting TGF-β1 expression was explored. Relationships among TGF-β1 andsex, age, tumor ...
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Coping and Quality of Life in Turkish Women Living with Ovarian Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: This study investigated the utilization of both problem and emotion focused coping strategiesand their association with aspects of quality of life among Turkish women with ovarian cancer undergoingchemotherapy. ...
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Low Expression of the FoxO4 Gene may Contribute to the Phenomenon of EMT in Non-small Cell Lung Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Because of its importance in tumor invasion and metastasis, the epithelial-mesenchymal transition (EMT)has become a research focus in the field of cancer. Recently, evidence has been presented that FoxO4 might beinvolved ...
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The Metabolic Syndrome is Associated with More Aggressive Prostate Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Purpose: The aim of this study was to analyze any association between the metabolic syndrome (MetS) andrisk of prostate cancer (PCa) and cancer grade among men undergoing radical prostatectomy for PCa. Materialsand ...
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Cisplatin Combined with Metformin Inhibits Migration and Invasion of Human Nasopharyngeal Carcinoma Cells by Regulating E-cadherin and MMP-9
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Metformin has been shown to be useful in reducing insulin resistance by restoring sensitivity. Recentevidence suggests that metformin might also possess anti-tumour activity. This study aimed to investigate theeffects of ...
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Diagnostic and Prognostic Value of miR-205 in Colorectal Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Emerging evidence has shown associations of microRNA-205 (miR-205) with crucial cell processes such as theepithelial-mesenchymal transition (EMT) and aberrant expression with tumorigenesis in many types of humanmalignancy. ...
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5-Fluorouracil and Interleukin-2 Immunochemotherapy Enhances Immunogenicity of Non-Small Cell Lung Cancer A549 Cells through Upregulation of NKG2D Ligands
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: The aim of this study was to investigate the anti-cancer effects and mechanisms ofimmunochemotherapy of 5-fluorouracil (5-FU) and interleukin-2 (IL-2) on non-small cell lung cancer (NSCLC)A549 cells. ...
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Perception of Breast Cancer Screening among Iranian Women without Experience of Mammography: A Qualitative Study
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: In Iran, there are high rates of breast cancer. It is among the five most common cancers, thefirst among cancers diagnosed, and is the leading cause of cancer deaths among Iranian women. Objectives: ...
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Human Papillomavirus Genotype Distribution and E6/ E7 Oncogene Expression in Turkish Women with Cervical Cytological Findings
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: Infection with certain human papillomavirus (HPV) genotypes is the most important riskfactor related with cervical cancer. The objective of the present study was to investigate the prevalence of HPVinfection, ...
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Curcumin Induces Apoptosis in SGC-7901 Gastric Adenocarcinoma Cells via Regulation of Mitochondrial Signaling Pathways
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Curcumin, a polyphenol compound derived from the rhizome of the plant Curcuma longa L. has been verifiedas an anticancer compound against several types of cancer. However, understanding of the molecular mechanismsby which ...
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Rapamycin and PF4 Induce Apoptosis by Upregulating Bax and Down-Regulating Survivin in MNU-Induced Breast Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: To elucidate the role of rapamycin and PF4 on apoptosis regulation via Bax (pro-apoptosis),Bcl-2 (anti-apoptosis) and survivin activation on the growth in the 1-methyl-1-nitrosourea -induced invasivebreast ...
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Overexpression of TRPM7 is Associated with Poor Prognosis in Human Ovarian Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: The melastatin-related transient receptor potential 7 channel (TRPM7) is a nonselectivecation channel that has been shown to promote tumor metastasis and progression. In this study, we determinedthe ...
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Un-met Supportive Care Needs of Iranian Breast Cancer Patients
(West Asia Organization for Cancer Prevention (WAOCP), 2014-09-01)Background: Assessment of supportive needs is the requirement to plan any supportive care program forcancer patients. There is no evidence about supportive care needs of Iranian breast cancer patients. So, the aimsof ...
