مرور Volume 20, Issue 12 بر اساس عنوان
در حال نمایش موارد 1 - 20 از 28
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AMPK Activation of Apoptotic Markers in Human Breast Cancer Cell Lines with Different p53 Backgrounds: MCF-7, MDA-MB-231 and T47D Cells
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: Downregulation of AMPK has been established as a major contributor to carcinogenesis in many types of human cancer. We sought to investigate the influence of activated AMPK on apoptotic markers in human breast ...
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Analysis of Decision Tree and K-Nearest Neighbor Algorithm in the Classification of Breast Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Objective: The death rate of breast tumour is falling as there is progress in its research area. However, it is the most common disease among women. It is a great challenge in designing a machine learning model to evaluate ...
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Angiogenesis and Lymphangiogenesis in Salivary Gland Adenoid Cystic Carcinoma and Mucoepidermoid Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background and Purpose: This study aimed to investigate the immunohistochemical expression of CD31 and podoplanin in order to examine angiogenesis and lymphangiogenesis, respectively in common malignant tumors of salivary ...
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Antibacterial and Anticancer Activities of Fenugreek Seed Extract
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)This work is about the utilization of fenugreek seed as an antibacterial and anticancer agents. The antibacterial activity of fenugreek seed extract on six pathological bacteria strains were specified through conventional ...
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Assessment of the Diagnostic Potential of miR-29a-3p and miR-92a-3p as Circulatory Biomarkers in Acute Myeloid Leukemia
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: Acute myeloid leukemia (AML) is a set of Myeloproliferative neoplasms that are identified by excessive growth of myeloid blasts and production of abnormal blood cells. AML is the most common type of acute ...
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Association of XPO1 Overexpression with NF-κB and Ki67 in Colorectal Cancer
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Objectives: Exportin 1(XPO1), a nuclear exporter protein, has been gaining recognition in cancer progression and treatment. This study aimed to evaluate the association between the overexpression of XPO1 with NF-κB, Ki67 ...
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Chlamydia Trachomatis Infection in High-Risk Human Papillomavirus Based on Cervical Cytology Specimen
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Objective: High-risk human papillomavirus (HR HPV) was associated with the development of cervical cancer. Asymptomatic Chlamydia trachomatis (C. trachomatis) infection is the most common bacterial, sexually-transmitted ...
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Delays in Diagnosis and Treatment of Breast Cancer and the Pathways of Care: A Mixed Methods Study from a Tertiary Cancer Centre in North East India
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Introduction: In India, mortality rate in breast cancer is high because more than half are diagnosed late at locally advanced or metastatic stages. This might be due to presentation delay (recognition of symptoms to first ...
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Design and Development of In-House Multichannel Applicator for HDR Vaginal Brachytherapy and Dosimetric Comparision with Single Channel Applicator
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Introduction: Endometrial cancer (EC) is a leading cause of female cancer in developed countries. The total abdominal hysterectomy and bilateral salpingo-oophorectomy with pelvic lymph node dissection is the primary ...
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Detection of Epithelial Ovarian Cancer using C8Magnetic Bead Separation and MALDI-TOF Plasma Proteome Profiling in Egyptian Females
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: Ovarian cancer is the seventh most common cancer in females with the highest mortality rate of all gynecological cancers due to its late discovery and ambiguous symptoms. Thus, there is a need for new promising ...
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Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: Radioresistance remains a challenge for cancer radiotherapy. The present study aims to investigate the role of TMPRSS4 in triple negative breast cancer (TNBC) cell radiosensitivity. Materials and Methods: After ...
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Effectiveness of a School-Based ‘Tobacco Free’ Intervention on Adolescents’ Knowledge and Exposure to Second Hand Tobacco Smoke - A Multiphase Study
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: There is no safe level of exposure to second hand tobacco smoke (SHS). The World Health Organization has stressed that 100% smoke-free environments are the only effective way to protect the population from the ...
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The Evaluation of Intra-Operative Frozen Section Diagnosis Accuracy of Ovarian Tumors; Old Fashioned Not Out of Fashion
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: The accuracy of intra-operative decision in confirming ovarian tumor malignancy during the operation is vital. Frozen sections are an important intra-operative tool to determine the provisional diagnosis and ...
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Exosomes as a Surrogate Marker for Autophagy in Peripheral Blood, Correlative Data from Phase I Study of Chloroquine in Combination with Carboplatin/Gemcitabine in Advanced Solid Tumors
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: Autophagy is a catabolic process, utilized constitutionally by body cells to recycle nutrients and to remove unwanted/damaged intracellular constituents. It is enhanced during periods of stress, such as starvation ...
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Forgone Health and Economic Benefits Associated with Socioeconomic Differences in Organized Cervical Cancer Screening
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Objective: To describe cervical cancer screening participation among women in Taiwan under its population-based screening policy and to estimate the economic burden of disease attributable to avoidable disparities in ...
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Is High Definition MLC Dosimetrically Superior to Standard Definition MLC for SIB-SBRT for Carcinoma Prostate
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Objective: The study was conducted to quantitatively evaluate the dosimetric effects of high definition (2.5 mm) and standard definition (5.0 mm) MLC on the quality of SBRT plans using SIB-IMRT and SIB-VMAT technique for ...
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JAK2 and Beyond: Mutational Study of JAK2V617 in Myeloproliferative Disorders and Haematological Malignancies in Kashmiri population
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: Janus Tyrosine Kinase-2 (JAK2 V617F), a novel point mutation affecting the MPD'S is a somatic gain-of-function mutation. It alters a highly conserved amino acid valine in the negative regulatory JH2 domain to ...
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Knowledge of Cancer Risk Factors, Symptoms, and Barriers to Seeking Medical Help among Omani Adolescents
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Objective: Raising cancer awareness among adolescents should lead to early diagnosis and improve their survival rate into adulthood. This study aims to identify knowledge of cancer risk factors, symptoms and barriers to ...
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Natural Killer Cell Expansion with Autologous Feeder Layer and Anti-CD3 Antibody for Immune Cell Therapy of Hepatocellular Carcinoma
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Background: one of the promising approaches for treatment of some cancers is adoptive cell therapy using natural killer (NK) cells. Various methods have been investigated for ex vivo expansion of NK cells in large-scale, ...
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Ovarian Cancer Incidence in the Multi-Ethnic Asian City-State of Singapore 1968-2012
(West Asia Organization for Cancer Prevention (WAOCP), 2019-12-01)Purpose: We investigate ovarian cancer incidence between 1968 and 2012 in Singapore, a multiethnic Asian city state. Methods: Aggregated data of ovarian epithelial cancer numbers and estimated person-years from 1968 to ...



