Background: Human papillomavirus (HPV) is one of the most common sexually transmitted infectionsworldwide and the association between HPV infection and genital cancers has been well established. This studyconcerned ...

Skin metastases of breast cancer are usually late events in the course of tumor progression and signify apoor prognosis. They may remain as a therapeutic challenge especially after failure of standard treatments.Topical ...

Background: An easy, reproducible and simple marker is needed to estimate phase of endometrial pathologiclesions such as hyperplasia and endometrial cancer and distinguish from pathologically normal results. Wehere ...

Background: Evidence shows direct link of HER2 to increased glycolysis and over production of lactatedehydrogenase (LDH). HER2 overexpression, high LDH and low glucose pleural levels are associated withpoor prognosis ...

Background: The prostaglandin-endoperoxide synthase 2 (PTGS2) and phospholipase A2 group IIA (PLA2G2A)genes encode enzymes that are involved in arachidonic acid and prostaglandin biosynthesis. Dysregulation ofboth ...

Objective: The main purpose of this work was to investigate the effect of berberine hydrochloride (BH) onthe proliferation, apoptosis, migration, and invasion of CNE-1 nasopharyngeal carcinoma cells. Our results ...

Spirogyra neglecta, a freshwater green alga, is a local food in the northern and northeastern parts of Thailand.This investigation explored the anticarcinogenicity of S neglecta and its possible cancer chemopreventivemechanisms ...

The life of a mother undergoes a dramatic change after a child is diagnosed with cancer. The present studyaimed to determine effects on the everyday life process and health status of mothers with children sufferingfrom ...

Objectives: MicroRNAs (miRNAs) are important regulators of many physiological and pathologicalprocesses, including tumorigenesis and metastasis. In this study, we sought to determine the underlying molecularmechanisms ...

Background: Breast cancer is the most common malignant tumor in females worldwide. Many differencesexist in clinico-pathological characteristics of breast cancer patients between China and Western countries. Thisstudy ...

Background: Published studies on clinical outcome of helical tomotherapy for lung cancer are limited. Thepurpose of this study was to evaluate clinical outcomes and treatment-related toxicity in inoperable non-smallcell ...

Background: To study the clinical presentation of cervical carcinoma correlating with histopathologicalfindings in a tertiary hospital situated in the southern part of India catering to rural and semi-urban ...

The rhabdomyosarcoma (RMS) is the most common type of soft tissue tumor in children and adolescents;yet only a few screens for oncogenic mutations have been conducted for RMS. To identify novel mutations andpotential ...

Development of drugs from natural products has been undergoing a gradual evoluation. Many plant derivedcompounds have excellent therapeutic potential against various human ailments. They are important sourcesespecially for ...

Background: Calprotectin in feces seems to be a more sensitive marker for gastrointestinal (GI) cancers thanfecal occult blood, but its specificity may be too low for screening average risk populations. This study ...

MicroRNAs are a class of small noncoding RNA which play important regulatory roles in a variety of cancers.MiRNA-specific expression profiles have been reported for several pathological conditions. In this study, wecombined ...

Background: Transient receptor potential melastatin 8 (TRPM8), a principle membrane receptor involved incalcium ion influx and cell signal transduction, has been found to be up-regulated in some cancer types, ...

Background: There is no standard treatment for patients with colorectal cancer (CRC) progressing afteririnotecan and oxaliplatin treatment. Here we aimed to retrospectively evaluate the efficacy and tolerability ...

Enhancing of radioresponsiveness of tumors by using radiosensitizers is a promising approach to increase theefficacy of radiation therapy. Recently, the ethanolic extract of the medicinal plant, Derris scandens Benth hasbeen ...