Background: The response to treatment and overall survival (OS) of patients with acute myeloid leukemia(AML) is variable, with a median ranging from 6 months to 11.5 years. TP53 is associated with old age,chemotherapy ...

Skin metastases of breast cancer are usually late events in the course of tumor progression and signify apoor prognosis. They may remain as a therapeutic challenge especially after failure of standard treatments.Topical ...

Background: The current standard treatment for patients with newly diagnosed diffuse large B cell lymphoma(DLBCL) is rituximab combined with cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP).A ...

The life of a mother undergoes a dramatic change after a child is diagnosed with cancer. The present studyaimed to determine effects on the everyday life process and health status of mothers with children sufferingfrom ...

Background: Human papillomavirus (HPV) is one of the most common sexually transmitted infectionsworldwide and the association between HPV infection and genital cancers has been well established. This studyconcerned ...

Objective: To find a more appropriate alternative to D-dimer cutoff value for the diagnosis of deep veinthrombosis (DVT) in cancer patients. Methods: A total of 711 cancer patients with symptoms ...

Background: Evidence shows direct link of HER2 to increased glycolysis and over production of lactatedehydrogenase (LDH). HER2 overexpression, high LDH and low glucose pleural levels are associated withpoor prognosis ...

Background: The prostaglandin-endoperoxide synthase 2 (PTGS2) and phospholipase A2 group IIA (PLA2G2A)genes encode enzymes that are involved in arachidonic acid and prostaglandin biosynthesis. Dysregulation ofboth ...

Background: Lymphoma is a malignant neoplasm of lymphoid tissue classified into Hodgkin’s and non-Hodgkin’s types. It mostly affects lymph nodes although a considerable proportion of Non-Hodgkin’s casesoccur in ...

Background: Colorectal cancer (CRC) is a leading cause of cancer death among Vietnamese Americans, yetscreening remains underutilized. We investigated the effectiveness of a culturally tailored DVD intervention ...

Aim: To investigate effects of sulforaphane on the BIU87 cell line and underlying mechanisms involvingIGFBP-3. Methods: Both BIU87 and IGFBP-3-silenced BIU87 cells were treated with sulforaphane. Cellproliferation ...

Background: Time to colposcopy (TC) after abnormal Pap smears was evaluated for influence on cytohistologiccorrelation (CHC). Materials and Methods: This retrospective study assessed the correlation ...

The present study conducted with 100 oral cancer patients at a private tertiary care hospital inDelhidemonstrated that stage III cancer was associated with longer use of tobacco and poor oral hygiene. Therewas also ...

Background: Breast cancer is the most common malignant tumor in females worldwide. Many differencesexist in clinico-pathological characteristics of breast cancer patients between China and Western countries. Thisstudy ...

Objective: The aim of this study was to screen for possible biomarkers of metastatic osteosarcoma (OS) using aDNA microarray. Methods: We downloaded the gene expression profile GSE49003 from Gene ...

Development of drugs from natural products has been undergoing a gradual evoluation. Many plant derivedcompounds have excellent therapeutic potential against various human ailments. They are important sourcesespecially for ...

Background: In clinical trials with no upper age limit, the proportion of older patients is usually small, probablyreflecting the more conservative approach adopted by clinicians when treating the elderly. An ...

The amplification of telomerase component (TERC) gene could play an important role in generation andtreatment of haematological malignancies. This present study was aimed to investigate copy number amplificationstatus of ...

Spirogyra neglecta, a freshwater green alga, is a local food in the northern and northeastern parts of Thailand.This investigation explored the anticarcinogenicity of S neglecta and its possible cancer chemopreventivemechanisms ...

The rhabdomyosarcoma (RMS) is the most common type of soft tissue tumor in children and adolescents;yet only a few screens for oncogenic mutations have been conducted for RMS. To identify novel mutations andpotential ...