Saffron (Crocus sativus) is one of the indigenous plants of Iran. Recently its possible effects have been reported on lipid abnormalities and oxidative stress. The aim of this study was to investigate the effects of saffron ...

Myelotoxicity remains the most important cause of life threatening complications in patients undergoing antineoplastic chemotherapy cycles. Strategies to circumvent or lessen myelotoxicity may improve clinical outcome and ...

Recently use of antifungal drugs in human medicine has been increased, especially with the advent of AIDS epidemic. Despite the growing list of azoles, their clinical value has been limited by their relatively high risk ...

Strychnine is a toxic alkaloid which might be the source of poisoning with homicidal and suicidal purposes. Eleven fatal cases of strychnine ingestion were considered in this study. Strychnine was isolated from biological ...

Captopril is an angiotensin converting enzyme inhibitor, which is used in hypertensive crises and heart failures as an emergency medication especially in pediatrics. Due to difficulty in swallowing of tablets and capsules, ...

Fulminant hepatic failure is a deleterious clinical complication, which leads to hyperammonemia. Ammonia is a noxious neurotoxic agent, which affects brain tissue through different mechanisms. On the other hand, it is ...

Hepatic encephalopathy (HE) is a serious clinical complication, which could lead to coma and death if not appropriately managed. There is agreement on the predominant role of ammonia in the etiology of HE. Brain is one of ...