مرور Volume 5, Issue 3 بر اساس تاریخ انتشار
در حال نمایش موارد 1 - 4 از 4
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Citrus aurantium (bitter orange) seeds oil: pharmacognostic, anti-inflammatory and anti-nociceptive properties
(Shiraz University of Medical Sciences, 2019-09-01)The present investigation was carried out to evaluate the pharmacognostic properties of Citrus aurantium seeds as well as its anti-inflammatory activities. The n-hexane fraction of seed oil extracted via a Soxhlet extractor ...
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Discovery of Potential Natural Dipeptidyl Peptidase-4 Inhibitors for Type-2 Diabetes Treatment via Structure-Based Virtual Screening
(Shiraz University of Medical Sciences, 2019-09-01)Dipeptidyl peptidase IV (DPP-4) is a serine protease that plays a crucial role in glucose metabolism; hence, it is a significant target for type II diabetes mellitus treatment. DPP-4 inhibitors decrease glucose concentrations ...
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The anti- proliferative effects of Ferulago angulata on human promyelocytic leukemia cell line (HL-60)
(Shiraz University of Medical Sciences, 2019-09-01)Aim: Ferulago angulata is a medicinal plant with bioactive compounds having antioxidant activities. F.angulata extract can be a good candidate as chemo- preventive agent against cancer cells. In this study, the pro-apoptotic ...
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Influence of quercetin and chrysin on the intestinal permeability of paclitaxel, a substrate of P-glycoprotein and CYP3A4 using in vitro rat gut sacs
(Shiraz University of Medical Sciences, 2019-09-01)P-glycoprotein (P-gp) and cytochrome P450 3A4 (CYP3A4) play a significant role in the disposition and elimination of drugs. The objective of this study was to investigate the mechanism underlying the interaction between ...
