Insulitis is the inflammation of beta cells of the Langerhans islets. It is well-known that insulitis is a prevalent complication of diabetes. A series of xenobiotics, including drugs, could also induce insulitis. The ...

The increased burden of cancer disease globally arouses the urgent need for the development of novel chemical agent with improved efficacy and potency which can provide selective therapeutic outcome to an individual cancer ...

Several chemotherapeutic agents have been associated with cancer treatment but with numerous adverse effects. In this study, the cytotoxic and antioxidant effects of methanol extracts of ten selected plants from Nigerian ...

Phenolic acids such as rosmarinic acid (RA) and caffeic acid (CA), are the most significant phenolic compounds in Lamiaceae family, including Salvia species. The aim of this study was to evaluate the RA and CA contents of ...

Pyranopyrazole analogs are novel synthetic compounds with many biological activities. In this research, we synthesized six new pyranopyrazole derivatives using a biocompatible catalyst and evaluated their vasorelaxant and ...

This study aimed to determine the phenolic acids contained in the stem of Sandoricum koetjape and to determine their inhibitory activity against the matrix metalloproteinase-9 (MMP-9). Sandoricum koetjape has been used for ...

Acne vulgaris is a very common skin problem. Cutibacterium acnes (formerly Propionibacterium acnes), a common skin organism, is most notably recognized for its role in acne vulgaris. Standard oral and topical treatments ...