Volume 26, Issue 1
مرور بر اساس
ارسال های اخیر
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Thymoquinone played a protective role against tartrazine-induced hepatotoxicity
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): The current study, the first of its kind in the literature, aimed to observe the toxic effects of Tartrazine, a commonly used dyestuff in industries and foods, on the liver, and investigate whether this ...
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Relationship of OqxAB efflux pump to antibiotic resistance, mainly fluoroquinolones in <i>Klebsiella pneumoniae</i>, isolated from hospitalized patients
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): This research was designed to study the prevalence of OqxAB efflux pump genes and also to investigate the relationship between efflux pump and resistance to antibiotics, especially to fluoroquinolones, evaluate ...
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Genome-wide DNA methylation dynamics in carbon tetrachloride-induced mice liver fibrosis
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): Many persistent harmful stimuli can result in chronic liver diseases, which lead to about 2 million deaths per year in the whole world. Liver fibrosis was found to exist in all kinds of chronic liver diseases. ...
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Elucidation of flavonoids from potent Iranian <i>Scutellaria</i> species against Influenza A (H1N1) virus
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): Influenza A virus (IAV) is a contagious illness. Different species of Scutellaria genus are used as a traditional remedy to reduce influenza symptoms. This study aimed to investigate the anti-influenza capacity ...
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Protective effect of melatonin on learning and memory impairment and hippocampal dysfunction in rats induced by high-fructose corn syrup
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): We investigated the harmful effects of high fructose corn syrup (HFCS) on learning and memory in the hippocampus and the ameliorative effects of melatonin (Mel). Materials and Methods: Thirty-six adult male ...
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Green synthesis of silver nanoparticles, graphene, and silver-graphene nanocomposite using <i>Melissa officinalis</i> ethanolic extract: Anticancer effect on MCF-7 cell line
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): Nanotechnology has helped a lot in diagnosing and treating multiple illnesses, specifically cancer, and increasing the development of targeted drug delivery methods. Nanocomposites are materials with at least ...
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Albiflorin alleviates DSS-induced ulcerative colitis in mice by reducing inflammation and oxidative stress
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): To clarify therapeutic potential of albiflorin and its intrinsic mechanisms against dextran sulfate sodium (DSS)-induced Ulcerative colitis (UC) mice.Materials and Methods: Sixty male C57BL/6 mice were randomly ...
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Simultaneous determination of mometasone furoate and calcipotriol in a binary mixture by validated HPLC and chemometric-assisted UV spectrophotometric methods and identification of degradation products by LC-MS
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): A new binary mixture containing mometasone furoate (MF) and calcipotriol (CP) is suggested to manage psoriasis; since the combined stability profile of these drugs is poorly understood.Materials and Methods: ...
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LSD1 in beige adipocytes protects cardiomyocytes against oxygen and glucose deprivation
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): Epicardial adipose tissue (EpAT) is known for its role in supporting the cardiomyocytes. Lysine-specific demethylase 1 (LSD1), a typical lysine demethylase, is an essential regulator for the maintenance of ...
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Vinpocetine’s immunomodulating, anti-oxidant, anti-inflammatory, ant-ifibrotic, and PDE inhibiting potencies ameliorate bleomycin-induced pulmonary fibrosis
(Mashhad University of Medical Sciences, 2023-01-01)Objective(s): Pulmonary fibrosis (PF) is a global health problem with a high economic burden. Intratracheal administration of bleomycin is the best model that resembles the pathogenesis of PF in humans. Recently, vinpocetine ...
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Ameliorative effects of <i>Portulaca oleracea</i> L. (purslane) and its active constituents on nervous system disorders: A review
(Mashhad University of Medical Sciences, 2023-01-01)Nowadays, the global interest in the use of herbal medicines and their main components in developing novel effective medications with fewer adverse effects is rising. Precise medicinal plants have potential advantageous ...
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Iranian Journal of Basic Medical Sciences: Pursuing the COPE membership
(Mashhad University of Medical Sciences, 2023-01-01)



