Antimicrobial activity of Hibiscus sabdariffal extract against human pathogen

Abstract

The purpose of this study was to examine the evolution of antimicrobial activity of flower extract of <em>Hibiscus sabdariffal</em> against antibiotic-resistant <em>Escherichia coli</em> and<em> Staphylococcus aureus</em> that isolates from the urinary tract infection by microtiterplate method. All 42 strains 30 <em>E.coli</em> and 12 <em>S. aureus</em> isolated from urine culture of hospitalized patients in Zabol ( Zabol, south-eastern Iran) suffered from urinary tract infections during the years 2011- 2012 were evaluated and the extract of <em>Hibiscus sabdariffal</em>obtained by rotary and the minimum inhibitory concentrations were investigated to characterize the antimicrobial activities of this extract. The result show that <em>E. coli</em> were resistance to 4 of the agent and more resistance to tetracyclin(63.3%), erythromycin(56.6%) and cefixime(40 %), <em>S.aureus</em> more sensitive were antibiotic resistance to vancomycin and cefixime. The highest MIC values was found to be 20mg/ml against two <em>E.coli</em>. The leas MIC values was found to 1.25 mg/ml against three <em>S.aureus</em>.