MCM-BP as a Novel Nanomagnetic Reusable Basic Catalyst for the one Pot Solvent-Free Synthesis of Dihydropyridine, Polyhydroquinoline and Polyhydroacridine Derivatives via Hantzsch Multicomponent Condensation Reaction

Abstract

<em><span>By the immobilization of </span><span>bipyridinium chloride</span><span> onto mesoporous MCM-41encapsulated </span><span>Fe₃O₄</span><span> nanoparticles via a simple post-synthesis method, a totally new organic-inorganic hybrid nanocomposite was formulated. The heterogeneous hybrid </span><span>nanomagnetic</span><span> composite was characterized by </span><span>Fourier Transform InfraRed (FT-IR), X-Ray powder Diffraction (XRD), Scanning Electron Microscope (SEM), Transmission Electron Microscope (TEM), Vibrating Sample Magnetometer (VSM</span><span>) and Thermal Gravimetric Analytical (TGA). </span><span>The potential applications </span><span>of this </span><span>novel nanomagnetic and recyclable basic </span><span>nanocomposite, </span><span>Fe₃O₄@MCM-BP</span><span>, were also investigated </span><span>for solvent-free synthesis of 1,4-dihydropyridine, polyhydroquinoline, and polyhydroacridine derivatives via Hantzsch multicomponent condensation reaction.</span><span> High isolated yields, operational simplicity, clean reaction conditions and minimum pollution of the environment, makes the procedure a useful and appealing process in organic transformation.</span></em>