Catalytic effect of green zinc oxide nanoparticles on multi –component reactions

Abstract

In this study, multi component Hantzsch reaction was carried out between various Aromatic Aldehyde with Dimedone,Ethyl acetateand ammonium acetate to produce polyhydroquinolinederivatives under solvent-free conditions at 110^oC by a (Zinc oxide nanocatalyst) as effective Lewis acid. The remarkable advantages offered by this method compared with other methods are a green catalyst, simple work-up procedures, fast reactions, a long high yields.