The study of anticariogenic effect of Silver nanoparticles for dental applications

Abstract

Dental caries is one of the most prevalent chronic diseases of people worldwide. In the development of caries a major role play bacteria of the <em>Streptococcus </em>and <em>Lactobacillus </em>genera which are acidogenic and aciduric. In this work, the antibacterial effect of silver nanoparticles was investigated on <em>Streptococcus mutans, Streptococcus sobrinus, Lactobacillus casei </em>and<em> Lactobacillus acidophilus </em>for inhibition and inactivation of cell growth. We successfully synthesized uniformly dispersed silver nanoparticles with a uniform size and shape using<em> salmonella typhirium</em>. The formation of silver nanoparticles was confirmed by UV-Visible spectrophotometer, dynamic light scattering (DLS) and transmission electron microscopy (TEM). Silver nanoparticles synthesized were in size ranging 4–11 nm with an average size of 7.5 nm. Silver nanoparticles exhibited high antibacterial activity against <em>S. mutans, S. sobrinus, L casei </em>and<em> L. acidophilus</em> and guided towards the fact that silver nanoparticles have emerged as a promising anticariogenic agent to treat dental diseases.