Synthesis and electrochemical studies on Cu-TiO2 thin films deposited by spray pyrolysis technique for sensing Uric acid

Abstract

In this study, we report an effective uric acid (UA) electrochemical biosensor using Cu-TiO₂electrode. UA is a biomedical compound that plays a vital role in human metabolism. The abnormal level of UA leads to several diseases. TiO₂ and Cu-TiO₂ with various concentrations were deposited on glass substrates by spray pyrolysis technique. The structural study shows by X-ray diffraction analysis shows that all the films are in anatase phase with tetragonal structure and confirm the incorporation of Cu ions into TiO₂ lattice. The morphology and chemical composition of TiO₂ and Cu-TiO₂ were characterized by scanning electron microscopy (SEM) and energy-dispersive x-ray spectroscopy (EDS). These studies reveal that the aggregation of particles occurs due to doping and confirm the presence of Cu. The optical analysis was studied by UV-Vis absorption and photoluminescence spectroscopy, which indicates the band gap changes, shift in absorption peak and defects. Cyclic voltammetry (CV) was used to analyse the performance of the Cu-TiO₂ as the electrochemical biosensor. Cu-TiO₂ electrochemical biosensor exhibits good sensitivity, linearity and high stability for the detection of UA.