An electrochemical acetaminophen sensor based on La3+/Co3O4 nanoflowers modified graphite screen printed electrode architecture

Abstract

In this study, the La³⁺/Co₃O₄ nanoflowers were synthesized by co-precipitation method. The morphology of the La³⁺/Co₃O₄NFs were characterized using scanning electron microscopy (SEM), and were further used to modify the graphite screen printed electrode (GSPE). The electrochemical behavior of acetaminophen at La³⁺/Co₃O₄NFs/GSPE has been studied in aqueous solutions. Experimental results showed that the La³⁺/Co₃O₄NFs modified GSPE possess excellent electrocatalytic activity toward the detection of acetaminophen. Under optimum conditions, the La³⁺/Co₃O₄NFs modified electrode exhibited high sensitivity and stability to acetaminophen over a wide linear range of concentrations from 0.5μM to 250.0μM, with a detection limit of 0.09μM. Finally, the proposed sensor was successfully applied to the detection of acetaminophen in real samples.