Volume 24, Issue 3
مرور بر اساس
ارسال های اخیر
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Association of <i>NOS3</i>-c.894G>T transversion with susceptibility to metabolic syndrome in Azar-cohort population: A case-control study and <i>in silico</i> analysis of the SNP molecular effects
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): We investigated whether NOS3-c.894G>T transversion (rs1799983), which causes the substitution of glutamate with aspartate (E298D) in the oxygenase domain of endothelial nitric oxide synthase (eNOS), is ...
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Correlation between antibiotic resistance and phylogenetic types among multidrug-resistant <i>Escherichia coli</i> isolated from urinary tract infections
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): Emergence of multidrug resistance has reduced the choice of antimicrobial regimens for UTIs. To understand the association of phenotype and genotype among uropathogens.Materials and Methods: Six hundred and ...
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Therapy with new generation of biodegradable and bioconjugate 3D printed artificial gastrointestinal lumen
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): Many patients die due to vascular, gastrointestinal lumen problems, and coronary heart diseases. Synthetic vessels that are made of biodegradable-nanofiber polymers have significant properties such as proper ...
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c-kit+ cells offer hopes in ameliorating asthmatic pathologies via regulation of miRNA-133 and -126
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): There are still challenges regarding c-kit+ cells' therapeutic outcome in the clinical setting. Here, we examined the c-kit+ cell effect on the alleviation of asthma by modulating miRNAs expression.Materials ...
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Designing and generating a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An <i>in silico</i> and <i>in vitro</i> study
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): IL-2Rα plays a critical role in maintaining immune function. However, expression and secretion of CD25 in various malignant disorders and autoimmune diseases are now well established. Thus, CD25 is considered ...
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Improved spatial memory, neurobehavioral outcomes, and neuroprotective effect after progesterone administration in ovariectomized rats with traumatic brain injury: Role of RU486 progesterone receptor antagonist
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): The contribution of classic progesterone receptors (PR) in interceding the neuroprotective efficacy of progesterone (P4) on the prevention of brain edema and long-time behavioral disturbances was assessed in ...
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Sustained release of linezolid in ocular insert based on lipophilic modified structure of sodium alginate
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): Ocular inserts are usually polymeric thin films with increased ocular residence time and sustained drug release capacity. Sodium alginate is a biocompatible and biodegradable carrier; however, initial burst ...
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Protective effects of selenium on electromagnetic field-induced apoptosis, aromatase P450 activity, and leptin receptor expression in rat testis
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): Electromagnetic field (EMF) emitted by mobiles may affect the male reproductive system. Selenium, as an antioxidant, may protect against electromagnetic field-induced tissue damage. Theis study aimed to ...
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Favorable effects of dill tablets and <i>Ocimum basilicum</i> L. extract on learning, memory, and hippocampal fatty acid composition in hypercholesterolemic rats
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): Hypercholesterolemia is correlated with brain amyloid-β (Aβ) deposition and impaired cognitive functions and contributes to Alzheimer's disease. Effects of cholesterol-lowering dill tablets and aqueous extract ...
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Thiamine reduced metabolic syndrome symptoms in rats via down-regulation of hepatic nuclear factor-kβ and induction activity of glyoxalase-I
(Mashhad University of Medical Sciences, 2021-03-01)Objective(s): Metabolic syndrome (MS) is a cause of death worldwide. The hepatic nuclear factor- NF-kβ (NF-kβ) is the cardinal player of hepatic homeostasis, insulin sensitivity, and lipid metabolism. Thus, we investigated ...
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The protective effect of <i>Azadirachta indica</i> (neem) against metabolic syndrome: A review
(Mashhad University of Medical Sciences, 2021-03-01)Metabolic syndrome is a condition associated with obesity, diabetes, dyslipidemia, and high blood pressure. Recently, the use of phytochemicals is suggested in the control and treatment of metabolic syndrome. The Azadirachta ...
