Cutaneous metastasis in a patient with adrenocortical carcinoma

Abstract

Adrenocortical carcinoma is an uncommon and aggressivemalignancy. Despite a high frequency of metastasis, cutaneousmetastasis of adrenocortical carcinoma is rare with only isolatedcase reports. Its diagnosis can be challenging based solely onhistopathological findings. Yet, the clinical history in combinationwith an immunohistochemical panel consisting of inhibin,vimentin, chromogranin, synaptophysin, melan- A, neuron specificenolase and calretinin, can be useful in differentiating it fromother tumours with similar morphology. We report a case of a52-year-old female who presented with subcutaneous noduleson her abdominal wall which, on histopathology, proved to bemetastasis from adrenocortical carcinoma diagnosed one and ahalf years ago.