Diffuse plane Xanthomatosis: A case report

Abstract

A 58-year-old man had 3 years history of asymptomatic, extensive, yellowish patches on his face, neck, trunk and arms. Histopathological examination confirmed the diagnosis of diffuse plane xanthomatosis. This is a rare non-lipemic disease in which xanthomatous lesions develop in the skin in association with paraproteinemia. Serum lipids are usually normal. The histological features include both xanthomatous and inflammatory elements. The treatment of this condition is that of the underlying myeloproliferative disease or paraproteinemia.