The effect of single bout of circuit resistance training on NT-proBNP levels in sedentary men

Abstract

Introduction: Cardiac natriuretic peptides (NPs) play an important role in the regulation of energy expenditure in skeletal muscle and adipose tissue. A systematic review on the effects of exercise on NPs in patients with heart failure reported that aerobic and resistance training reduced NPs; however, the effects of exercise on NPs and the underlying mechanism of exercise-induced NP secretion in sedentary subjects remain unknown. The aim of this study was to determine the effect of a single bout of circuit resistance training on aminoterminal propeptide (NT-proBNP) levels in sedentary men. Material & Methods: In this study, Fifteen healthy male (aged: 24.5 ± 1.2 years; ± SD) volunteered to participate in this study. The subjects were performed circuit resistance training consisted of 8 stations in the following order: chest press, barbell shoulder press, seated cable rows, barbell curl, overhead triceps extension, curl up, squat and hamstring with machine. This training was circularly performed in 8 stations and included 4 sets with 6 maximal repetitions at 70% of 1-RM in each station. Each circuit and set was separated by 5 min and 30 s rest respectively. NT-proBNP plasma concentrations were measured before and immediately after the resistance training. Paired-sample t- test was used to analyze the data. Results: The results demonstrated that NT-proBNP levels were increased significantly after the circuit resistance training (27.76% and P=0.01). Conclusions: In conclusion, a single bout of circuit resistance training in sedentary men led to a fast rise of plasma NT-proBNP concentrations.