Biginelli Multicomponent Condensation Reaction Promoted by 4,4ʹ-Bipyridinium Dichloride Ordered Mesoporous Silica Nanocomposite under Solvent Free Conditions

Abstract

In this paper, 4,4ʹ-bipyridinium dichloride supported SBA-15 (SBA@BiPy²⁺ 2Cl^-) was used for the synthesis of dihydropyrimidinones. The synthesized catalyst was characterized by FT-IR spectroscopy, scanning electron microscopy (SEM), Transmission electron microscopy (TEM) and Thermogravimetric analysis (TGA). This nanocomposite was shown to be an efficient heterogeneous catalyst for the synthesis of dihydropyrimidinones derivatives <em>via </em>one-pot multicomponent method under solvent-free conditions. In addition, the catalyst can be recycled several times with no significant loss of catalytic activity.