A Facile and Efficient Synthesis of Tetrahydrobenzo[b]pyrans Using Sucrose as Green, Inexpensive, Natural and Biodegradable Catalyst

Abstract

A very efficient one-pot three-component synthesis of pyran derivatives has been improved by condensation of aldehydes and malononitrile with dimedone under 80 °C using sucrose as natural and biodegradable catalyst in water. This method offers some advantages including inexpensive, high to quantitative yields, short reaction time, and easy work-up. Therefore, this methodology is entirely green and environmentally benign protocol for the preparation of tetrahydrobenzo[<em>b</em>]pyran derivatives.