Synthesis, Characterization and <i>in Vitro</i> Antibacterial Activities of CdO Nanoparticle and Nano-sheet Mixed-ligand of Cadmium(ІІ) Complex

Abstract

Here, we report the synthesis of a Schiff-base mixed-ligand complex of cadmium(ІІ) in bulk and nano-scales via the precipitation and sonochemical methods, respectively. The complex formula is [Cd(3-bpdh)(3-bpdb)Cl2]n (1), where the ligands are 3-bpdh = 2,5-bis(3-pyridyl)-3,4-diaza-2,4-hexadiene and 3-bpdb = 1,4-bis(3-pyridyl)-2,3-diaza-1,3-butadiene. The structure of mixed-ligand complex (1) was characterized by IR, 1H NMR and elemental analyses. Cadmium(ІІ) oxide nanoparticles were prepared by direct thermolysis from nanosheet of complex (1). The cadmium(ІІ) oxide structure was characterized by X-ray Diffraction (XRD) and Energy Dispersive X-ray analyses (EDAX). Size, morphology and structural dispersion of all obtained nanostructures were characterized by Scanning Electron Microscopy (SEM). The Schiff-base ligands, bulk and nano-scales of complex (1) and cadmium(ІІ) oxide nanoparticles were analyzed for antibacterial activities against Bacillus alvei (bacteria causing the honey bee European foulbrood disease). The Minimum Inhibitory Concentrations (MIC) has been shown moderate antibacterial activities compared with some other standard drugs. Known antibiotics like penicillin and SXT (Trimethoprim/sulfamethoxazole) were used as positive control.