Antimicrobial activity of Prosopis farcta L. and Datura stramonium L. extracts against Staphylococcus aureus

Abstract

<strong>Background & Aim: </strong>The aim of this study was to investigate the antimicrobial activity of two rangeland-medical plants extracts, <em>Prosopis</em> <em>farcta</em> L. and <em>Datura stramonium</em> L., against <em>Staphylococcus aureus</em> isolated from sheep in Zabol city.<br /> <strong>Experimental: </strong>The <em>P. farcta</em> and <em>D. stramonium</em> were collected from the rangelands of Zabol city. <em>Staphylococcus aureus</em> strains were isolated from the nose of sheep in Zabol city. Antibiotic resistance pattern was determined by Kirby Bauer method. Finally, the minimum inhibitory concentration (MIC) and minimum bactericide concentration (MBC) were determined by microdilution method.<br /> <strong>Results: </strong>The results of this study showed that the <em>P.farcta</em> extract had a MIC of 25 ppm, and 10 strains of the bacterium were inhibited in this concentration. The lowest inhibitory concentration of <em>D.stramonium</em> extract was 6.25 ppm, and one strain was inhibited in this concentration. On the other hand, the highest inhibitory concentration was 50 ppm and the highest bactericide concentration was 100 ppm.<br /> <strong>Recommended applications/ industries:</strong> The results of this study showed good antimicrobial effects of <em>D. stramonium </em>and<em> P. farcta</em> extracts that can be used to treat <em>Staphylococcus aureus</em> infections.