Electrochemical Approach for Determination of Tertahydrozoline HCl Using Gold nanoparticles Electrode
چکیده
The electrochemical behavior of tetrahydrozoline (THZ) was explored by cyclic voltammetry and differential pulse voltammetry. A well-defined peak at 915 mV using gold nanomodified electrode (AuNPts/CP) in presence of sodium dodecyl sulphate (SDS) was detected. Different buffers, pH and scan rates on oxidation peak current were studied. Linear calibration curve was achieved in the range of 1.99×10−5 to 7.79×10-5 M with a limit of detection (LOD) 5.54×10-6 M and limit of quantification (LOQ) 1.69×10−5 M, respectively.The suggested method was successfully utilized to the eye drops dosage form and urine sample with percentage recovery, 98.86%±0.77, and 101.13±0.62, respectively.
کلید واژگان
TetrahydrozolineVoltammetry
Gold nanoparticles
Carbon paste
surfactant
Electroanalysis
شماره نشریه
2تاریخ نشر
2020-02-011398-11-12
ناشر
University of Tehranسازمان پدید آورنده
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, University of Tanta, El Geish St., Tanta, El gharbeya, EgyptNational Organization for Drug Control and Research (NODCAR), 6 Abu Hazem Street, Pyramids Ave, P.O. 29, Cairo, Egypt
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, University of Tanta, El Geish St., Tanta, El gharbeya, Egypt
National Organization for Drug Control and Research (NODCAR), 6 Abu Hazem Street, Pyramids Ave, P.O. 29, Cairo, Egypt
National Organization for Drug Control and Research (NODCAR), 6 Abu Hazem Street, Pyramids Ave, P.O. 29, Cairo, Egypt
