Left Ventricular Clot due to Wild-Type Homozygous Factor V Leiden Mutation: A Case Report

Abstract

Factor V Leiden (FVL) mutation has been identified as a frequent risk factor for life-threatening venous thromboembolic events. We describe a 39-year-old man admitted with sudden-onset blurred vision and mild lower-limb paresthesia with a positive activated protein C resistance test. The polymerase chain reaction confirmed wild-type homozygous FVL mutation. Transthoracic echocardiography revealed a highly elongated mobile mass attached to the akinetic cardiac apex, which extended to the left ventricular outflow tract. The thrombosis was removed by thrombectomy through aortotomy. The patient was in good clinical condition atthe last follow-up. (Iranian Heart Journal 2015;16(3):57-59)