Chemical composition, antibacterial and antioxidant profile of essential oil from Murraya koenigii (L.) leaves

Abstract

Objective: This study is designed to extract and examine chemical composition, antimicrobial and antioxidant activity of the hydro-distillated essential oil of <em>Murraya koenigii</em> leaves from the south region of Tamilnadu, India. <br/>Matherials and Methods: Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis of the essential oil result was indicates the 33 different compounds representing 97.56 % of the total oil. <br/>Results: Major compounds detected in the oil were Linalool (32.83%), Elemol (7.44%), Geranyl acetate (6.18%), Myrcene (6.12%), Allo-Ocimene (5.02), α-Terpinene (4.9%), and (E)-β-Ocimene (3.68%) and Neryl acetate (3.45%). From the identified compounds, they were classified into four groups that are oxygenated monoterpenes (72.15%), monoterpene hydrocarbons (11.81%), oxygenated sesquiterpenes (10.48%) and sesquiterpenes hydrocarbons (03.12%). The antibacterial activity of essential oil has pronounced by Disc Diffusion Method against various pathogenic microbes. <br/>Conclusion: The oil has a maximum zone of inhibition ability against <em>Corynebacterium tuberculosis, Pseudomonas aeruginosa, Streptococcus pyogenes, Klebsiella pneumonia</em> and <em>Enterobacter aerogenes.</em> The antioxidant profile of the sample was determined by different test systems. In all the systems, essential oil showed a strongest activity profile within the concentration range.