EFFECT OF ADDING NEOSTIGMINE IN PARAVERTEBRAL BLOCK ON POSTOPERATIVE EXTUBATION TIME IN ELECTIVE CORONARY ARTERY BYPASS GRAFT SURGERY

Abstract

Introduction: Paravertebral block is a technique of regional anesthesia and is used for a number of purposes. The aim of this study was to assess the effects of adjuvant neostigmine in paravertebral block with bupivacaine for in coronary artery bypass grafting surgery (CABG).<br />Materials and methods: In total, 68 patients were randomly assigned into two groups: bupivacaine alone (B group) and bupivacaine with neostigmine (BN group) for bilateral paravertebral thoracic block at T6 level. Postoperative times for extubation, morphine requirements, and acute pain scores were assessed.<br />Results: The BN group patients were extubated sooner. Also, they needed less morphine in the first twenty-four hours.<br />Discussion: The study suggests that adding neostigmine to bupivacaine in paravertebral block as an adjuvant can have beneficial postoperative effects in patients undergoing elective CABG.