Electrospinning Nanofibers Gelatin scaffolds: Nanoanalysis of properties and optimizing the process for tissue engineering functional

Abstract

Electrospinning has been recognized as an efficient technique for the fabrication of polymer<br />nanofibers. Recently, various polymers have successfully been electrospun into ultrafine fibers.<br />Electrospinning is an extremely promising method for the preparation of tissue engineering scaffolds.<br />In this study, nanofibers gelatin was electrospun at 20% v/v optimized content. To produce gelatin<br />nanofibers optimally, production parameters need to be investigated. In the electrospinning, device<br />(voltage and distance) parameters were determined to be effective; as a result, these parameters<br />were researched and the influences of electrospinning device parameters (voltage & distance)<br />on properties of gelatin nanofibers were evaluated. These parameters affected the diameter<br />size, uniformity, hydrophilicity and thermal degradation of electrospun gelatin nanofibers. All of<br />these properties were examined by SEM, FTIR, CA, BET, XRAY and TGA tests and finally optimum<br />gelatin nanofibers can be used in many applications including cell culture, drug delivery and tissue<br />engineering.