Synthesis of a new Ag supported on hydroxyapatite-core-shell-γ-Fe2O3 nanoparticles (γ-Fe2O3@HAp-Ag NPs) and its application as a Lewis acid catalyst in the preparation of β-azidoalcohols and β-thiocyanohydrins from epoxides

Abstract

In this study, we synthesized Ag supported on hydroxyapatite-core-shell-<em>γ</em>-Fe₂O₃ nanoparticles (<em>γ</em>-Fe₂O₃@HAp-Ag NPs) as a new, lewis acid, and reusable heterogeneous nancatalyst. Then, it was successfully used for the synthesis of <em>β</em>-azido alcohols and <em>β</em>-thiocyanohydrins from the regioselective conversation of some epoxides by azide and thiocyanate anions in water. The reaction afforded the corresponding products with high regioselectivity under mild reaction conditions.