Volume 18, Issue 11
مرور بر اساس
ارسال های اخیر
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Dietary saffron reduced the blood pressure and prevented remodeling of the aorta in L-NAME-induced hypertensive rats
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):The aim of this study was to investigate the effects of nutritional saffron (Crocus sativus L.) stigma hydroalcoholic extract on blood pressure (BP) and histology of the aorta in ...
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Lavandula angustifolia extract improves deteriorated synaptic plasticity in an animal model of Alzheimer’s disease
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):Neurodegenerative Alzheimer's disease (AD) is associated with profound deficits in synaptic transmission and synaptic plasticity. Long-term potentiation (LTP), an experimental form of synaptic plasticity, ...
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The role of noggin in regulation of high glucose-induced apoptosis and insulin secretion in INS-1 rat beta cells
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):The purpose of this study was to investigate the effects of Noggin on high glucose-induced apoptosis and insulin secretion in pancreatic beta cells. Materials and Methods: Different ...
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Comparison of the effects of resveratrol and caloric restriction on learning and memory in juvenile C57BL/6J mice
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s): Both caloric restriction (CR) and resveratrol (RSV) have been shown to improve learning and memory, but their potential effects in juvenile animals were unknown. Here, we evaluated the effects of RSV ...
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Interactions of smoking with rs833061 polymorphism on the risk of non-alcoholic fat liver disease in Hubei Han population: a preliminary case–control study
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):Vascular endothelial growth factor (VEGF) has biological actions on energy homeostasis, inflammation and insulin resistance. The present study aimed to investigate the association between VEGF -460 ...
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Influence of vitamin D on cell cycle, apoptosis, and some apoptosis related molecules in systemic lupus erythematosus
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):Genetic and environmental factors are involved in the pathogenesis of systemic lupus erythematosus (SLE). Autoreactive lymphocytes are cleared through apoptosis and any disturbance in the apoptosis ...
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Rs401681 polymorphism in TERT-CLPTM1L was associated with bladder cancer risk: A meta-analysis
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):Genome-wide association studies have identified a number of genetic variants of telomerase reverse transcriptase (TERT), cleft lip and palate transmembrane1-like (CLPTM1L) associated with the risk of ...
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Establishment of a novel rat model of severe acute cholangitis
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):This study aimed to establish a novel non-binding, reversible rat model of acute cholangitis of the severe type (ACST). Materials and Methods:Twenty-six rats were randomly divided into ...
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Effect of exogenous leptin on serum levels of lipids, glucose, renal and hepatic variables in both genders of obese and streptozotocin-induced diabetic rats
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s): Leptin exerts various effects on appetite and body weight. Disruption of the obesitygene is precedent to fatness. Insulin or glucose elevates leptin, but streptozotocin reduces it. However, controversial ...
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Improving the neuronal differentiation efficiency of umbilical cord blood-derived mesenchymal stem cells cultivated under appropriate conditions
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s): Umbilical cord blood-derived mesenchymal stromal cells (UCB-MSCs) are ideally suited for use in various cell-based therapies. We investigated a novel induction protocol (NIP) to improve the neuronal ...
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Is adalimumab protective in ischemia-reperfusion injury in lung?
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I-R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor-alpha (TNF-α) inhibitor agent. ...
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Interaction of cholesterol ester transfer protein polymo- rphisms, body mass index, and birth weight with the risk of dyslipidemia in children and adolescents: the CASPIAN-III study
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s): This study aims to investigate joint association between cholesterol ester transfer protein (CETP) polymorphisms and body mass index (BMI) or birth weight with the risk of dyslipidemia in Iranian ...
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Effects of prenatal exposure to different colors on offsprings mood
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):There is much evidence indicating that depression is influenced by the levels of neurotransmitters such as dopamine, GABA and adrenaline. The current study we designed to investigate the ...
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Resveratrol protects against diet-induced atherosclerosis by reducing low-density lipoprotein cholesterol and inhibiting inflammation in apolipoprotein E-deficient mice
(Mashhad University of Medical Sciences, 2015-11-01)Objective(s):Resveratrol (RES) is a polyphenol compound that has been shown a promising cardioprotective effect. However, some reports have yielded conflicting findings. Herein, we investigated the anti-atherosclerotic ...
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Review of the traditional uses, phytochemistry, pharmacology and toxicology of giant fennel (Ferula communis L. subsp. communis)
(Mashhad University of Medical Sciences, 2015-11-01)Ferula communis L., subsp. communis, namely giant fennel, has extensively been used in traditional medicine for a wide range of ailments. Fresh plant materials, crude extracts and isolated components of ...
