Volume 17, Issue 9
مرور بر اساس
ارسال های اخیر
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The effects of co-administration of opium and morphine with nicotine during pregnancy on spatial learning and memory of adult male offspring rats
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s): Smoking opium/cigarette is a global health concern. The aim of this study was to examine learning and memory of rat male offsprings whose mothers had been exposed to either opium or morphine with ...
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Green tea extract protects endothelial progenitor cells from oxidative insult through reduction of intracellular reactive oxygen species activity
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s):Many studies have reported that tea consumption decreases cardiovascular risk, but the mechanisms remain unclear. Green tea is known to have potent antioxidant and free radical ...
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Effect of thoracic epidural blockade on hypoxia-induced pulmonary arterial hypertension in rats
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s): The present study was aimed to investigate the influence of thoracic epidural blockade on hypoxia-induced pulmonary hypertension in rats. Materials and Methods: Forty eight Wistar rats were ...
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Association of ADAM33 gene polymorphisms with allergic asthma
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s): Asthma results from the interaction between genetic and environmental factors. ADAM33 gene on chromosome 20p13 is associated with asthma and airway hyperresponsiveness. Materials and ...
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Preparation and characterization of PLGA nanospheres loaded with inactivated influenza virus, CpG-ODN and Quillaja saponin
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s): The purpose of this study was preparation and evaluation of PLGA nanospheres containing ...
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Cloning and expression of the enzymatic region of Streptococcal hyaluronidase
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s): Streptococcus pyogenes produces extracellular hyaluronidase enzyme. This enzyme is directly associated with the spread of the organism during infection. The objective of the present ...
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Glucose concentration in culture medium affects mRNA expression of TRPV1 and CB1 receptors and changes capsaicin toxicity in PC12 cells
(Mashhad University of Medical Sciences, 2014-09-01)Objective (s):Hyperglycemia is widely recognized as the underlying cause for some debilitating conditions in diabetic patients. The role of cannabinoid CB1 and vanilloid TRPV1 receptors and their endogenous agonists, ...
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Comparison of human adipose-derived stem cells and chondroitinase ABC transplantation on locomotor recovery in the contusion model of spinal cord injury in rats
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s):Spinal cord injury (SCI) is one of the most serious clinical diseases and its treatment has been a subject of interest to researchers. There are two important therapeutic strategies in the treatment ...
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Plasma levels of leptin and visfatin in rheumatoid arthritis patients; is there any relationship with joint damage?
(Mashhad University of Medical Sciences, 2014-09-01)Objective (s):Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder, primarily targeting the synovium and articular cartilage that leads to joint damage. Recent reports have suggested the role of ...
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Synthesis and docking analysis of new heterocyclic system of tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b]quinolines as aldose reductase inhibitors
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s):In recent years, the chemistry of Tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b]quinolines have received considerable attention owing to their synthetic and effective biological importance which ...
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Surface protein mutations in chronic hepatitis B patients who received hepatitis B vaccine therapy
(Mashhad University of Medical Sciences, 2014-09-01)Objective (s):The aim of this study was to determine the correlation between vaccine therapy and appearance of mutations in hepatitis B surface antigen (HBsAg)-positive chronic hepatitis B virus (HBV) patients. ...
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Alpha-1 antitrypsin, retinol binding protein and keratin 10 alterations in patients with psoriasis vulgaris, a proteomic approach
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s):Psoriasis is an autoimmune disease that appears on the skin. Although psoriasis is clinically and histologically well characterized, its pathogenesis is unknown in detail. The aims of this study were ...
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Molecular characterization of Aspergillus infections in an Iranian educational hospital using RAPD-PCR method
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s): The nosocomial infections by Aspergillus species are associated with constructions and increased dust loads in hospital indoors. Our main object was to find the environmental sources of Aspergillus ...
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New insight into the immunomodulatory mechanisms of Tretinoin in NMRI mice
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s):Recent evidence have proposed that Tretinoin produced in the gut preferentially promote differentiation of FoxP3+Treg cells but inhibits Th17 lymphocytes, and this may be the main immunomdulatory ...
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The mitochondrial DNA mutations associated with cardiac arrhythmia investigated in an LQTS family
(Mashhad University of Medical Sciences, 2014-09-01)Objective(s): As mitochondrial oxidative stress is probably entailed in ATP production, a candidate modifier factor for the long QT syndrome (LQTS) could be mitochondrial DNA (mtDNA). It has been notified ...
