Volume 17, Issue 5
مرور بر اساس
ارسال های اخیر
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Evaluation of urinary enzymes in newborns treated with gentamicin
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s): In recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. We examined the practical applicability of the urinary ...
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Genetic properties of blaCTX-M and blaPER β-lactamase genes in clinical isolates of Enterobacteriaceae by polymerase chain reaction
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):blaCTX-Mand blaPER are two genes that encode class A extended-spectrum β-lactamases (ESBLs) and can be responsible for therapeutic problems. This study was ...
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Testicular morphology of male rats exposed to Phaleria macrocarpa (Mahkota dewa) aqueous extract
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):This study was designed to investigate the effect of Phaleria macrocarpa aqueous extract (PM) on spermatogenesis by observing the histological changes of testes in adult male rats. ...
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Genetic polymorphisms of glutathione-s-transferase M1 and T1 genes with risk of diabetic retinopathy in Iranian population
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):To the best of our knowledge, this is the first report on the contributions of GST genetic variants to the risk of diabetic retinopathy in an Iranian population. Therefore, the objective of this study ...
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Matrix-mini-tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s): The aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. Materials and Methods:
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Evaluation of synthetic zeolites as oral delivery vehicle for anti-inflammatory drugs
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s): In this research, zeolite X and zeolite Y were used as vehicle to prepare intestine targeted oral delivery systems of indomethacin and ibuprofen. Materials and Methods: A soaking procedure ...
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Mutations in pre-core and basal-core promoter regions of hepatitis B virus in chronic HBV patients from Golestan, Iran
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s): It has been reported that the mutation of the pre-core (PC) and basal-core promoter (BCP) may play an important role in the development of HBV-related hepatocellular carcinoma (HCC). In this study ...
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Effect of temperature on wet agglomeration of crystals
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):This study dealt with the wet agglomeration process in which a small quantity of binder liquid was added into a suspension of crystals, directly in the stirring vessel where the crystallization took ...
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Allopregnanolone suppresses diabetes-induced neuropathic pain and motor deficit through inhibition of GABAA receptor down-regulation in the spinal cord of diabetic rats
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):Painful diabetic neuropathy is associated with hyperexcitability and hyperactivity of spinal cord neurons. However, its underlying pathophysiological mechanisms have not been fully clarified. Induction ...
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Preparation and characterization of celecoxib solid dispersions; comparison of poloxamer-188 and PVP-K30 as carriers
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):Solid dispersion formulation is the most promising strategy to improve oral bioavailability of poorly water soluble drugs. The aim of this study was to compare the effect of polyvinylpyrrolidone K30 ...
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Values of troponin T and myoglobin predictive of non-cardiac ischemia in rats
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):Biochemical markers are important for the timely diagnosis and follow-up of ischemic events. Most of the markers have been previously studied in the context of cardiac ischemia. However, research on ...
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Glutathione s-transferase M1 and T1 genetic polymorphisms in Iranian patients with glaucoma
(Mashhad University of Medical Sciences, 2014-05-01)Objective(s):Glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. Glutathione S-transferases (GSTs) are members of multigenic family, which have important ...



