Volume 23, Issue 1
مرور بر اساس
ارسال های اخیر
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Chronic consumption of cassava juice induces cellular stress in rat substantia nigra
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Cassava (Manihot esculenta Crantz) contains cyanogenic glycosides (linamarin and lotaustralin) that have been associated with neurological disorders in humans and rats. In basal ...
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Effect of vitamin D supplementation on CREB-TrkB-BDNF pathway in the hippocampus of diabetic rats
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Cyclic AMP (adenosine monophosphate) response element-binding protein (CREB) and Brain-derived neurotrophic factor (BDNF) are reported to broadly involve in learning capacity and ...
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Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Exposure to electromagnetic fields (EMF) emitted from mobile phones may cause a deleterious effect on human health and may affect the male reproductive system. Crocin, a carotenoid ...
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Investigating the role of acute and repeated stress on remote ischemic preconditioning-induced cardioprotection
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): To study the effect of acute and repeated stress on cardioprotection-induced by remote ischemic preconditioning (RIPC).Materials and Methods: RIPC was ...
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Exercise training attenuates diabetes-induced cardiac injury through increasing miR-133a and improving pro-apoptosis/anti-apoptosis balance in ovariectomized rats
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): The useful and effective role of exercise program to prevent cardiac tissue apoptosis and fibrosis in ovariectomized type 2 diabetic (T2DM) rats (OVR.D) is well known. The current ...
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Neuronal injury and death following focal mild brain injury: The role of network excitability and seizure
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): While traumatic brain injury (TBI) is a predisposing factor for development of post-traumatic epilepsy (PTE), the occurrence of seizures following brain trauma can infuriate adverse ...
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Effect of crocin, an active saffron constituent, on ethanol toxicity in the rat: histopathological and biochemical studies
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): The drinking of ethanol causes the wide range of clinical illness and morphological changes including hepatotoxicity and nephrotoxicity. In the current study, the protective properties ...
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Iranian Journal of Basic Medical Sciences: 2019 in retrospect
(Mashhad University of Medical Sciences, 2020-01-01)
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Role of crocin in several cancer cell lines: An updated review
(Mashhad University of Medical Sciences, 2020-01-01)Cancer is a major public health problem worldwide. The most important considerable features of cancer cells are uncontrolled proliferation, up-regulated differentiation, and immortality. Crocin, as a bioactive compound of ...
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The preventive effect of atorvastatin on liver fibrosis in the bile duct ligation rats via antioxidant activity and down-regulation of Rac1 and NOX1
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Atorvastatin is a cholesterol-lowering agent capable of inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase. Recent studies have demonstrated new facets of atorvastatin, such ...
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Effects of rabbit pinna-derived blastema cells on tendon healing
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Tendon healing is substantially slow and often associated with suboptimal repair. Cell therapy is one of the promising methods to improve tendon repair. Blastema, a population of ...



