Volume 23, Issue 1
مرور بر اساس
ارسال های اخیر
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Biological behaviors of muscarinic receptors in mesenchymal stem cells derived from human placenta and bone marrow
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Cells perform their functional activities by communicating with each other through endogenous substances and receptors. Post-translation, stem cells function properly in new host ...
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<i>Streptococcus pyogenes</i> strains associated with invasive and non-invasive infections present possible links with <i>emm</i> types and superantigens
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Streptococcus pyogenes, a notorious human pathogen is responsible to cause a wide range of infections varies from superficial common clinical illness to severe and life threatening ...
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Vitamin E therapy prevents the accumulation of congophilic amyloid plaques and neurofibrillary tangles in the hippocampus in a rat model of Alzheimer’s disease
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Vitamin E may have beneficial effects on oxidative stress and Aβ-associated reactive oxygen species production in Alzheimer's disease. But, the exact role of vitamin E as a treatment ...
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Chronic consumption of cassava juice induces cellular stress in rat substantia nigra
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Cassava (Manihot esculenta Crantz) contains cyanogenic glycosides (linamarin and lotaustralin) that have been associated with neurological disorders in humans and rats. In basal ...
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Effect of vitamin D supplementation on CREB-TrkB-BDNF pathway in the hippocampus of diabetic rats
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Cyclic AMP (adenosine monophosphate) response element-binding protein (CREB) and Brain-derived neurotrophic factor (BDNF) are reported to broadly involve in learning capacity and ...
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Protective effect of crocin on electromagnetic field-induced testicular damage and heat shock protein A2 expression in male BALB/c mice
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Exposure to electromagnetic fields (EMF) emitted from mobile phones may cause a deleterious effect on human health and may affect the male reproductive system. Crocin, a carotenoid ...
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Investigating the role of acute and repeated stress on remote ischemic preconditioning-induced cardioprotection
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): To study the effect of acute and repeated stress on cardioprotection-induced by remote ischemic preconditioning (RIPC).Materials and Methods: RIPC was ...
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Effect of crocin, an active saffron constituent, on ethanol toxicity in the rat: histopathological and biochemical studies
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): The drinking of ethanol causes the wide range of clinical illness and morphological changes including hepatotoxicity and nephrotoxicity. In the current study, the protective properties ...
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Possible protective effects of resveratrol in hepatocellular carcinoma
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Resveratrol (RSV) is a naturally occurring plant polyphenol with cardioprotective, neuroprotective, immunoregulatory, and anticancer properties and is biologically effective against ...
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Exercise training attenuates diabetes-induced cardiac injury through increasing miR-133a and improving pro-apoptosis/anti-apoptosis balance in ovariectomized rats
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): The useful and effective role of exercise program to prevent cardiac tissue apoptosis and fibrosis in ovariectomized type 2 diabetic (T2DM) rats (OVR.D) is well known. The current ...
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Neuronal injury and death following focal mild brain injury: The role of network excitability and seizure
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): While traumatic brain injury (TBI) is a predisposing factor for development of post-traumatic epilepsy (PTE), the occurrence of seizures following brain trauma can infuriate adverse ...
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A silent outbreak due to <i>Klebsiella pneumoniae</i> that co-produced NDM-1 and OXA-48 carbapenemases, and infection control measures
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Infections due to carbapenemase-producing Klebsiella pneumoniae are associated with high morbidity and mortality. In this study, we report a hospital outbreak due to co-producing ...
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Therapeutic effects of organic zinc on reproductive hormones, insulin resistance and <i>mTOR</i> expression, as a novel component, in a rat model of PCOS
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Zinc is an effective factor in the reproductive system. Insulin resistance (IR) is known as an important disorder in patients with polycystic ovary syndrome (PCOS). Mammalian target ...
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The preventive effect of atorvastatin on liver fibrosis in the bile duct ligation rats via antioxidant activity and down-regulation of Rac1 and NOX1
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Atorvastatin is a cholesterol-lowering agent capable of inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase. Recent studies have demonstrated new facets of atorvastatin, such ...
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Dietary phytate lowers <i>K-ras</i> mutational frequency, decreases DNA-adduct and hydroxyl radical formation in azoxymethane-induced colon cancer
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Dietary phytate is known to protect against azoxymethane (AOM)-induced preneoplastic lesions. The present study was designed to determine whether dietary phytate affects mutation ...
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Effects of rabbit pinna-derived blastema cells on tendon healing
(Mashhad University of Medical Sciences, 2020-01-01)Objective(s): Tendon healing is substantially slow and often associated with suboptimal repair. Cell therapy is one of the promising methods to improve tendon repair. Blastema, a population of ...
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Role of crocin in several cancer cell lines: An updated review
(Mashhad University of Medical Sciences, 2020-01-01)Cancer is a major public health problem worldwide. The most important considerable features of cancer cells are uncontrolled proliferation, up-regulated differentiation, and immortality. Crocin, as a bioactive compound of ...
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Iranian Journal of Basic Medical Sciences: 2019 in retrospect
(Mashhad University of Medical Sciences, 2020-01-01)



