Volume 18, Issue 1
مرور بر اساس
ارسال های اخیر
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Time course changes of oxidative stress and inflammation in hyperoxia-induced acute lung injury in rats
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s):Therapies with high levels of oxygen are commonly used in the management of critical care. However, prolonged exposure to hyperoxia can cause acute lung injury. Although oxidative stress and inflammation ...
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Expression of melanocortin-4 receptor and agouti-related peptide mRNAs in arcuate nucleus during long term malnutrition of female ovariectomized rats
(Mashhad University of Medical Sciences, 2015-01-01)Objective: Melanocortin-4 receptor (MC4R) and agouti-related peptide (AgRP) are involved in energy homeostasis in the rat. The aim of the present study was to evaluate the expression of MC4R and AgRP mRNAs in ...
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Experimental therapeutic studies of Solanum aculeastrum Dunal. on Leishmania major infection in BALB/c mice
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s):Solanum acueastrum Dunal.has been shown to have some chemotherapeutic value. Leaf and berry water and methanol compounds of S. acueastrum were evaluated for possible antileishmanial ...
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In vitro differentiation of rat mesenchymal stem cells to hepatocyte lineage
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s): Mesenchyme is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm. Recently, mesenchymal stem cells (MSCs), as adult stem cells (ASCs) able to divide into a variety ...
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MEFV mutations in Northwest of Iran: a cross sectional study
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s):Familial Mediterranean Fever (FMF) is an autosomal recessive disorder characterized by recurrent episodes of fever accompanied by peritonitis, pleurisy, and arthritis. FMF affects mainly Mediterranean ...
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Liver ischemia preconditions the heart against ischemia-reperfusion arrhythmias
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s):This study aimed to examine the hypothesis that an antiarrhythmic effect might be obtained by ischemic preconditioning of the liver, and also to characterize the potential underlying mechanisms. ...
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Safranal-loaded solid lipid nanoparticles: evaluation of sunscreen and moisturizing potential for topical applications
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s): In the current study, sunscreen and moisturizing properties of solid lipid nanoparticle (SLN)-safranal formulations were evaluated. Materials and Methods:Series of SLN were prepared ...
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Ellagic acid improves hyperalgesia and cognitive deficiency in 6-hydroxidopamine induced rat model of Parkinson’s disease
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s):Parkinson's disease (PD) is known for motor impairments. But often, there are non-motor symptoms such as cognitive deficiency and pain misperception, owing to possible role of nigrostriatal pathway. ...
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In silico and in vitro studies of cytotoxic activity of different peptides derived from vesicular stomatitis virus G protein
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s):This study aims at exploring cytotoxic activity of different peptides derived from VSVG protein against MCF-7 and MDA-MB-231 breast cancer cell lines and human embryonic kidney normal cell (HEK 293). ...
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Human Wharton’s jelly-derived mesenchymal stem cells express oocyte developmental genes during co-culture with placental cells
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s): The present day challenge is how to obtain germ cells from stem cells to treat patients with cancer and infertility. Much more efforts have been made to develop a procedure for attaining germ cells ...
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Helicobacter pylori in Iran: A systematic review on the antibiotic resistance
(Mashhad University of Medical Sciences, 2015-01-01)Objective(s):Helicobacter pylori (H. pylori) is a pathogenic bacterium that colonizes the stomachs of approximately 50% of the world's population. Resistance of H. pylori to antibiotics ...
