A fast, simple and convenient procedure for the synthesis of fused pyrimidinone derivatives by using [Hmim][HSO4] as a green, efficient and reusable catalyst under solvent-free conditions
چکیده
In the present of methylimidazolium hydrogen sulfate, the synthesis of arylidene heterobicyclic pyrimidinones is studied by condensation of aromatic aldehyde, cyclopentanone, and urea or thiourea. Using solvent-free conditions, non-toxic and inexpensive materials, simple and clean work-up, short reaction times and good yields of the products are the advantages of this method.
کلید واژگان
PyrimidinoneMethylimidazolium hydrogen sulfate
Bronsted acidic ionic liquid
Biginelli-type reaction
شماره نشریه
4تاریخ نشر
2012-12-011391-09-11
ناشر
Islamic Azad University, Shahreza Branchسازمان پدید آورنده
Department of Science, Khorasgan Branch, Islamic Azad University, Isfahan 81595-158, Iran.Department of Science, Fasa Branch, Islamic Azad University, Post Box No 364, Fasa, 7461713591, Fars, Iran.
Department of Pharmacology, University of Wisconsin, Medical School, 1300 University Avenue, Madison, 53706-1532, WI, USA. Pharmaceutical Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, IR Iran.
Department of Science, Najafabad Branch, Islamic Azad University, Isfahan, Iran.
شاپا
2252-02362345-4865
